Abnormal sodium and water homeostasis in mice with defective heparan sulfate polymerization.
Glycosaminoglycans in the skin interstitium and endothelial surface layer have been shown to be involved in local sodium accumulation without commensurate water retention. Dysfunction of heparan sulfate glycosaminoglycans may therefore disrupt sodium and water homeostasis. In this study, we investig...
Main Authors: | Rik H G Olde Engberink, Judith de Vos, Angela van Weert, Yahua Zhang, Naomi van Vlies, Bert-Jan H van den Born, Jens M Titze, Ed van Bavel, Liffert Vogt |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0220333 |
Similar Items
-
Perturbed body fluid distribution and osmoregulation in response to high salt intake in patients with hereditary multiple exostoses
by: Jetta J. Oppelaar, et al.
Published: (2021-12-01) -
Heparan sulfates and heparan sulfate binding proteins in sepsis
by: Yi-En Liao, et al.
Published: (2023-02-01) -
The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells.
by: Dipanwita Mitra, et al.
Published: (2021-08-01) -
The Effects of Heparan Sulfate Infusion on Endothelial and Organ Injury in a Rat Pneumosepsis Model
by: Daan P. van den Brink, et al.
Published: (2023-10-01) -
ScFv anti-heparan sulfate antibodies unexpectedly activate endothelial and cancer cells through p38 MAPK: implications for antibody-based targeting of heparan sulfate proteoglycans in cancer.
by: Helena C Christianson, et al.
Published: (2012-01-01)