Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China
Bin Lu,1 Yunzhen Shi,1 Yangxiao Zhou,2 Fenhua Zhao,3 Mengqi Wang,4 Xinling Pan5 1Department of Infectious Diseases, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical Un...
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Dove Medical Press
2022-10-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/case-report-the-first-case-of-bloodstream-infection-complicated-with-p-peer-reviewed-fulltext-article-IDR |
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| author | Lu B Shi Y Zhou Y Zhao F Wang M Pan X |
| author_facet | Lu B Shi Y Zhou Y Zhao F Wang M Pan X |
| author_sort | Lu B |
| collection | DOAJ |
| description | Bin Lu,1 Yunzhen Shi,1 Yangxiao Zhou,2 Fenhua Zhao,3 Mengqi Wang,4 Xinling Pan5 1Department of Infectious Diseases, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 3Department of Radiology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 4Department of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 5Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of ChinaCorrespondence: Xinling Pan, Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, No. 60 Wuningxi Road, Dongyang, Zhejiang, People’s Republic of China, Tel +86-0579-86859825, Fax +86-0579-86856878, Email panfengyuwuzu@163.comAbstract: Aggregatibacter aphrophilus is part of the normal flora in the oropharynx and upper respiratory tract, which causes invasive bacteremia in rare cases. However, the culture and identification of Aggregatibacter aphrophilus are challenging, hence easily misdiagnosed or undetected in clinical practice. In this case, a 73-year-old male patient was admitted to the hospital with a fever and right hip pain. Routine blood and C-reactive protein tests showed abnormal inflammatory markers. Positive blood culture revealed the presence of Aggregatibacter aphrophilus through mass spectrometry. The computed tomography examination further revealed the presence of psoas abscess, pulmonary infection, and pleural effusion, which was relieved by ceftriaxone combined with levofloxacin therapy, the drainage of psoas abscess and pleural effusion. Therefore, since multiple anatomic sites infection, including bloodstream, psoas abscess and pulmonary infection caused by Aggregatibacter aphrophilus, is rare, sufficient attention should be paid to its clinical diagnosis and treatment.Keywords: Aggregatibacter aphrophilus, blood stream, psoas abscess, pulmonary infection |
| first_indexed | 2024-04-12T12:46:11Z |
| format | Article |
| id | doaj.art-9da74946f21a4c1caf755e08ef544f64 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-12T12:46:11Z |
| publishDate | 2022-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-9da74946f21a4c1caf755e08ef544f642022-12-22T03:32:37ZengDove Medical PressInfection and Drug Resistance1178-69732022-10-01Volume 155953595778960Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in ChinaLu BShi YZhou YZhao FWang MPan XBin Lu,1 Yunzhen Shi,1 Yangxiao Zhou,2 Fenhua Zhao,3 Mengqi Wang,4 Xinling Pan5 1Department of Infectious Diseases, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 2Department of Clinical Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 3Department of Radiology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 4Department of Neurology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of China; 5Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, People’s Republic of ChinaCorrespondence: Xinling Pan, Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, No. 60 Wuningxi Road, Dongyang, Zhejiang, People’s Republic of China, Tel +86-0579-86859825, Fax +86-0579-86856878, Email panfengyuwuzu@163.comAbstract: Aggregatibacter aphrophilus is part of the normal flora in the oropharynx and upper respiratory tract, which causes invasive bacteremia in rare cases. However, the culture and identification of Aggregatibacter aphrophilus are challenging, hence easily misdiagnosed or undetected in clinical practice. In this case, a 73-year-old male patient was admitted to the hospital with a fever and right hip pain. Routine blood and C-reactive protein tests showed abnormal inflammatory markers. Positive blood culture revealed the presence of Aggregatibacter aphrophilus through mass spectrometry. The computed tomography examination further revealed the presence of psoas abscess, pulmonary infection, and pleural effusion, which was relieved by ceftriaxone combined with levofloxacin therapy, the drainage of psoas abscess and pleural effusion. Therefore, since multiple anatomic sites infection, including bloodstream, psoas abscess and pulmonary infection caused by Aggregatibacter aphrophilus, is rare, sufficient attention should be paid to its clinical diagnosis and treatment.Keywords: Aggregatibacter aphrophilus, blood stream, psoas abscess, pulmonary infectionhttps://www.dovepress.com/case-report-the-first-case-of-bloodstream-infection-complicated-with-p-peer-reviewed-fulltext-article-IDRaggregatibacter aphrophilusblood streampsoas abscesspulmonary infection |
| spellingShingle | Lu B Shi Y Zhou Y Zhao F Wang M Pan X Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China Infection and Drug Resistance aggregatibacter aphrophilus blood stream psoas abscess pulmonary infection |
| title | Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China |
| title_full | Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China |
| title_fullStr | Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China |
| title_full_unstemmed | Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China |
| title_short | Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused by Aggregatibacter aphrophilus in China |
| title_sort | case report the first case of bloodstream infection complicated with psoas abscess and pulmonary infection caused by aggregatibacter aphrophilus in china |
| topic | aggregatibacter aphrophilus blood stream psoas abscess pulmonary infection |
| url | https://www.dovepress.com/case-report-the-first-case-of-bloodstream-infection-complicated-with-p-peer-reviewed-fulltext-article-IDR |
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