Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC‐Derived Embryonic Stage Mesodermal Precursor Cells

Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC‐Derived Embryonic Stage Mesodermal Precursor Cells

Abstract The selection of pluripotent stem cell (PSC)‐derived cells for tissue modeling and cell therapy will be influenced by their response to the tissue environment, including the extracellular matrix (ECM). Whether and how instructive memory is imprinted in adult ECM and able to impact on the ti...

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Bibliographic Details
Main Authors: Imran Ullah, Jonas Felix Busch, Anja Rabien, Bettina Ergün, Christof Stamm, Christoph Knosalla, Stefan Hippenstiel, Petra Reinke, Andreas Kurtz
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Advanced Science
Subjects:
cell differentiation
extracellular matrix
pluripotent stem cells
regenerative medicine
tissue engineering
Online Access:https://doi.org/10.1002/advs.201901198

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