Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus
Aims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) re...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2012-12-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5536 |
| _version_ | 1797255228092841984 |
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| author | Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev |
| author_facet | Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev |
| author_sort | Olga Leonidovna Barbarash |
| collection | DOAJ |
| description | Aims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) received follow-up for cardiovascular events during12 months after an episode of unstable angina pectoris. Upon hospitalization for acute coronary syndrome analyses wereperformed to assess the degree of systemic inflammation evaluating plasma concentration of pro- and anti-inflammatorymarkers (CRP, fibrinogen, IL-6, -8, -10, TNF-?), as well as blood glucose and glycated haemoglobin HbA1c. Results. TNF-? and IL-6 levels were significantly higher in patients with unfavorable prognosis (p |
| first_indexed | 2024-03-08T15:21:33Z |
| format | Article |
| id | doaj.art-9da962cc12024b6d9cf14ec7c8fa8432 |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:02:31Z |
| publishDate | 2012-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-9da962cc12024b6d9cf14ec7c8fa84322024-03-20T11:47:58ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782012-12-01154394510.14341/2072-0351-55365494Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitusOlga Leonidovna Barbarash0Aleksey Nikolaevich Sumin1Olesya Evgen'evna Avramenko2Anastasia Vyacheslavovna Osokina3Aleksey Vladimirovich Veremeev4Research Institute for complex issues of cardiovascular diseases, Kemerovo; Kemerovo State Medical Academy, KemerovoResearch Institute for complex issues of cardiovascular diseases, KemerovoResearch Institute for complex issues of cardiovascular diseases, KemerovoResearch Institute for complex issues of cardiovascular diseases, KemerovoResearch Institute for complex issues of cardiovascular diseases, KemerovoAims. Our study was aimed to assess the influence of non-specific inflammation and endothelial dysfunction on developmentof cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and progressive angina pectoris. Materials and methods. 140 patients (63 of them were also diabetic) received follow-up for cardiovascular events during12 months after an episode of unstable angina pectoris. Upon hospitalization for acute coronary syndrome analyses wereperformed to assess the degree of systemic inflammation evaluating plasma concentration of pro- and anti-inflammatorymarkers (CRP, fibrinogen, IL-6, -8, -10, TNF-?), as well as blood glucose and glycated haemoglobin HbA1c. Results. TNF-? and IL-6 levels were significantly higher in patients with unfavorable prognosis (phttps://www.dia-endojournals.ru/jour/article/view/5536unstable anginanon-specific inflammationunfavorable prognosisdiabetes mellitus |
| spellingShingle | Olga Leonidovna Barbarash Aleksey Nikolaevich Sumin Olesya Evgen'evna Avramenko Anastasia Vyacheslavovna Osokina Aleksey Vladimirovich Veremeev Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus Сахарный диабет unstable angina non-specific inflammation unfavorable prognosis diabetes mellitus |
| title | Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_full | Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_fullStr | Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_full_unstemmed | Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_short | Prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| title_sort | prognostic significance of proinflammatory factors in patients with progressive angina pectoris and type 2 diabetes mellitus |
| topic | unstable angina non-specific inflammation unfavorable prognosis diabetes mellitus |
| url | https://www.dia-endojournals.ru/jour/article/view/5536 |
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