Maternal serum perlecan levels in women with preeclampsia
Objective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perl...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-01-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2019.1711390 |
| _version_ | 1797681532562833408 |
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| author | Murat Akbas Faik Mumtaz Koyuncu Burcu Artunc-Ulkumen Fatma Taneli Habib Ozdemir |
| author_facet | Murat Akbas Faik Mumtaz Koyuncu Burcu Artunc-Ulkumen Fatma Taneli Habib Ozdemir |
| author_sort | Murat Akbas |
| collection | DOAJ |
| description | Objective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies. Conclusion: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia. |
| first_indexed | 2024-03-11T23:46:11Z |
| format | Article |
| id | doaj.art-9daba05341a640fd99a45ff3234d9d65 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:46:11Z |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-9daba05341a640fd99a45ff3234d9d652023-09-19T09:24:43ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652020-01-01391707610.1080/10641955.2019.17113901711390Maternal serum perlecan levels in women with preeclampsiaMurat Akbas0Faik Mumtaz Koyuncu1Burcu Artunc-Ulkumen2Fatma Taneli3Habib Ozdemir4Manisa Celal Bayar UniversityManisa Celal Bayar UniversityManisa Celal Bayar UniversityManisa Celal Bayar UniversityManisa Celal Bayar UniversityObjective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies. Conclusion: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia.http://dx.doi.org/10.1080/10641955.2019.1711390preeclampsiaperlecansevere preeclampsia |
| spellingShingle | Murat Akbas Faik Mumtaz Koyuncu Burcu Artunc-Ulkumen Fatma Taneli Habib Ozdemir Maternal serum perlecan levels in women with preeclampsia Hypertension in Pregnancy preeclampsia perlecan severe preeclampsia |
| title | Maternal serum perlecan levels in women with preeclampsia |
| title_full | Maternal serum perlecan levels in women with preeclampsia |
| title_fullStr | Maternal serum perlecan levels in women with preeclampsia |
| title_full_unstemmed | Maternal serum perlecan levels in women with preeclampsia |
| title_short | Maternal serum perlecan levels in women with preeclampsia |
| title_sort | maternal serum perlecan levels in women with preeclampsia |
| topic | preeclampsia perlecan severe preeclampsia |
| url | http://dx.doi.org/10.1080/10641955.2019.1711390 |
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