B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat
Primary lymphoma of the middle ear is rare in cats, and little information has been accumulated on the treatment and course. An 11-year-old spayed female mixed-breed cat was brought to our hospital with facial nerve paralysis, which had been stable using prednisolone for 3 months. She was diagnosed...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/10/9/585 |
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| author | Tomoko Takahashi Hiroyuki Nagata Hirotaka Kondo |
| author_facet | Tomoko Takahashi Hiroyuki Nagata Hirotaka Kondo |
| author_sort | Tomoko Takahashi |
| collection | DOAJ |
| description | Primary lymphoma of the middle ear is rare in cats, and little information has been accumulated on the treatment and course. An 11-year-old spayed female mixed-breed cat was brought to our hospital with facial nerve paralysis, which had been stable using prednisolone for 3 months. She was diagnosed with B-cell lymphoma of the right middle ear after otoscopic sampling, which showed evidence of the filling of bilateral tympanic bullae on computed tomography. Hepatic involvement was suspected, and she was treated with multidrug chemotherapy, resulting in clinical remission. On day 176, magnetic resonance imaging and computed tomography were performed at checkup, revealing tumor invasion into the nasopharyngeal region and the recurrence of hepatic lesions without any brain abnormality. Nasal congestion then worsened, and the patient died on day 228 after presenting with generalized seizures. Clinicians should be mindful of middle ear lymphoma as a differential diagnosis in cats who present with a sign of otitis media, especially whose condition does respond to corticosteroid treatment. The prognosis for feline middle ear lymphoma might not be as poor as previous reports, and multidrug chemotherapy might result in remission of the disease. |
| first_indexed | 2024-03-10T21:52:44Z |
| format | Article |
| id | doaj.art-9dad07560d824a02a3d6e2755f26255c |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T21:52:44Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-9dad07560d824a02a3d6e2755f26255c2023-11-19T13:21:11ZengMDPI AGVeterinary Sciences2306-73812023-09-0110958510.3390/vetsci10090585B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a CatTomoko Takahashi0Hiroyuki Nagata1Hirotaka Kondo2Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa 2520880, Kanagawa, JapanNoppo Animal Hospital, 2-12-2 Okamoto, Kamakura 2470072, Kanagawa, JapanDepartment of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa 2520880, Kanagawa, JapanPrimary lymphoma of the middle ear is rare in cats, and little information has been accumulated on the treatment and course. An 11-year-old spayed female mixed-breed cat was brought to our hospital with facial nerve paralysis, which had been stable using prednisolone for 3 months. She was diagnosed with B-cell lymphoma of the right middle ear after otoscopic sampling, which showed evidence of the filling of bilateral tympanic bullae on computed tomography. Hepatic involvement was suspected, and she was treated with multidrug chemotherapy, resulting in clinical remission. On day 176, magnetic resonance imaging and computed tomography were performed at checkup, revealing tumor invasion into the nasopharyngeal region and the recurrence of hepatic lesions without any brain abnormality. Nasal congestion then worsened, and the patient died on day 228 after presenting with generalized seizures. Clinicians should be mindful of middle ear lymphoma as a differential diagnosis in cats who present with a sign of otitis media, especially whose condition does respond to corticosteroid treatment. The prognosis for feline middle ear lymphoma might not be as poor as previous reports, and multidrug chemotherapy might result in remission of the disease.https://www.mdpi.com/2306-7381/10/9/585facial nervehypoglossal nervelymphomanasopharyngeal polypotitis mediaprednisolone |
| spellingShingle | Tomoko Takahashi Hiroyuki Nagata Hirotaka Kondo B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat Veterinary Sciences facial nerve hypoglossal nerve lymphoma nasopharyngeal polyp otitis media prednisolone |
| title | B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat |
| title_full | B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat |
| title_fullStr | B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat |
| title_full_unstemmed | B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat |
| title_short | B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat |
| title_sort | b cell lymphoma of the middle ear treated with multidrug chemotherapy in a cat |
| topic | facial nerve hypoglossal nerve lymphoma nasopharyngeal polyp otitis media prednisolone |
| url | https://www.mdpi.com/2306-7381/10/9/585 |
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