Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24

Members of the Ebolavirus genus demonstrate a marked differences in pathogenicity in humans with Ebola (EBOV) being the most pathogenic, Bundibugyo (BDBV) less pathogenic, and Reston (RESTV) is not known to cause a disease in humans. The VP24 protein encoded by members of the Ebolavirus genus blocks...

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Bibliographic Details
Main Authors: Palaniappan Ramanathan, Bersabeh Tigabu, Rodrigo I. Santos, Philipp A. Ilinykh, Natalia Kuzmina, Olivia A. Vogel, Naveen Thakur, Hamza Ahmed, Chao Wu, Gaya K. Amarasinghe, Christopher F. Basler, Alexander Bukreyev
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
Ebolavirus
VP24
immune evasion
STAT1
Online Access:https://www.mdpi.com/1999-4915/15/5/1075

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