Severity of COVID-19 and Treatment Strategy for Patient With Diabetes

Coronavirus disease 2019 (COVID-19), which was named by the World Health Organization (WHO) in February 2020, has quickly spread to more than 200 countries around the world and was declared as a global pandemic in March 2020. The severity of the disease makes it more prone to severe symptoms and hig...

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Main Authors: Shi Jin, Weina Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.602735/full
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author Shi Jin
Weina Hu
author_facet Shi Jin
Weina Hu
author_sort Shi Jin
collection DOAJ
description Coronavirus disease 2019 (COVID-19), which was named by the World Health Organization (WHO) in February 2020, has quickly spread to more than 200 countries around the world and was declared as a global pandemic in March 2020. The severity of the disease makes it more prone to severe symptoms and higher mortality rates in patients, especially those who are with comorbidities, including high blood pressure, cardiovascular disease, obesity, and diabetes, increases the concern over the consequences of this pandemic. However, initial reports do not clearly describe whether diabetes itself or associated comorbidities or treatment strategies contribute to the severe prognosis of COVID-19 infections. Various clinical trials are being conducted on glucose-lowering agents but to date, there is no standard treatment protocol approved for COVID-19 cases with pre-existing diabetes. This review is aimed to decipher the potential risk factors of COVID-19 involved from existing evidence. Identification of a novel therapeutic strategy could be beneficial for combating SARS-CoV-2, which might be dreadful to debilitating people who have diabetes.
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spelling doaj.art-9dafda7808944bc0aa08fc189a91ef5a2022-12-21T22:27:45ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-04-011210.3389/fendo.2021.602735602735Severity of COVID-19 and Treatment Strategy for Patient With DiabetesShi Jin0Weina Hu1Department of Endocrinology, The Fourth Affiliated Hospital of China Medical University, Shenyang, ChinaDepartment of Cardiology, The Fourth Affiliated Hospital of China Medical University, Shenyang, ChinaCoronavirus disease 2019 (COVID-19), which was named by the World Health Organization (WHO) in February 2020, has quickly spread to more than 200 countries around the world and was declared as a global pandemic in March 2020. The severity of the disease makes it more prone to severe symptoms and higher mortality rates in patients, especially those who are with comorbidities, including high blood pressure, cardiovascular disease, obesity, and diabetes, increases the concern over the consequences of this pandemic. However, initial reports do not clearly describe whether diabetes itself or associated comorbidities or treatment strategies contribute to the severe prognosis of COVID-19 infections. Various clinical trials are being conducted on glucose-lowering agents but to date, there is no standard treatment protocol approved for COVID-19 cases with pre-existing diabetes. This review is aimed to decipher the potential risk factors of COVID-19 involved from existing evidence. Identification of a novel therapeutic strategy could be beneficial for combating SARS-CoV-2, which might be dreadful to debilitating people who have diabetes.https://www.frontiersin.org/articles/10.3389/fendo.2021.602735/fullDiabetes mellitusCOVID-19SARS-CoV-2cytokine stormglycemic control
spellingShingle Shi Jin
Weina Hu
Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
Frontiers in Endocrinology
Diabetes mellitus
COVID-19
SARS-CoV-2
cytokine storm
glycemic control
title Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
title_full Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
title_fullStr Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
title_full_unstemmed Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
title_short Severity of COVID-19 and Treatment Strategy for Patient With Diabetes
title_sort severity of covid 19 and treatment strategy for patient with diabetes
topic Diabetes mellitus
COVID-19
SARS-CoV-2
cytokine storm
glycemic control
url https://www.frontiersin.org/articles/10.3389/fendo.2021.602735/full
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