Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism

Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism

Although conventional immunohistochemistry for neurotropic rabies virus (RABV) usually shows high preference for neurons, non-neuronal cells are also potential targets, and abortive astrocyte infection is considered a main trigger of innate immunity in the CNS. While in vitro studies indicated diffe...

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Detalles Bibliográficos
Main Authors: Madlin Potratz, Luca Zaeck, Michael Christen, Verena te Kamp, Antonia Klein, Tobias Nolden, Conrad M. Freuling, Thomas Müller, Stefan Finke
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2020-02-01
Series:Cells
Subjects:
rabies
udisco
3d imaging
rabies pathogenicity
astrocyte infection
Acceso en liña:https://www.mdpi.com/2073-4409/9/2/412

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