Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage

Intraocular lymphoma (IOL) is a rare and life-threatening condition whose aetiology is unclear. Blurred vision, reduced vision, and floaters are common initial symptoms. Posterior vitreous detachment and haemorrhage rarely occur. The authors present the case of a 79-year-old man who initially prese...

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Main Authors: Catarina Pestana Santos, Rosa Alves, Bruno Sousa, Ana Cláudia Vieira, Tiago Judas
Format: Article
Language:English
Published: SMC MEDIA SRL 2022-12-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/3622
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author Catarina Pestana Santos
Rosa Alves
Bruno Sousa
Ana Cláudia Vieira
Tiago Judas
author_facet Catarina Pestana Santos
Rosa Alves
Bruno Sousa
Ana Cláudia Vieira
Tiago Judas
author_sort Catarina Pestana Santos
collection DOAJ
description Intraocular lymphoma (IOL) is a rare and life-threatening condition whose aetiology is unclear. Blurred vision, reduced vision, and floaters are common initial symptoms. Posterior vitreous detachment and haemorrhage rarely occur. The authors present the case of a 79-year-old man who initially presented with a 3-month history of fever, night sweats, significant weight loss, bilateral peri-orbital haematoma, red eyes and retro-orbital headache. Physical examination revealed fever, bilateral peri-orbital haematoma, subconjunctival haemorrhage and palpable cervical lymphadenopathy. CT scans detected conical intra-orbital lesions, cervical adenomegalies, expansive lesions in the adrenal glands, and thrombosis of the splenomesenteric confluent and posterior segment of the right branch of the portal vein. These findings were suggestive of a lymphoproliferative disorder. Aspiration cytology of the adrenal mass and inguinal adenopathies was compatible with diffuse large B-cell lymphoma with areas of transformation to Burkitt’s lymphoma. We describe a rare form of lymphoma, and a very unusual presentation of primary intraocular lymphoma with atypical symptoms.
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spelling doaj.art-9db0c0a84e2f460992aa1d985b4aab602023-01-10T15:02:27ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942022-12-0110.12890/2022_0036223157Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular HaemorrhageCatarina Pestana Santos0Rosa Alves1Bruno Sousa2Ana Cláudia Vieira3Tiago Judas4Internal Medicine Department, Hospital Garcia de Orta, Almada, Lisbon, PortugalInternal Medicine Department, Hospital Garcia de Orta, Almada, Lisbon, PortugalInternal Medicine Department, Hospital Garcia de Orta, Almada, Lisbon, PortugalPneumology Department, Hospital Garcia de Orta, Almada, Lisbon, PortugalInternal Medicine Department, Hospital Garcia de Orta, Almada, Lisbon, PortugalIntraocular lymphoma (IOL) is a rare and life-threatening condition whose aetiology is unclear. Blurred vision, reduced vision, and floaters are common initial symptoms. Posterior vitreous detachment and haemorrhage rarely occur. The authors present the case of a 79-year-old man who initially presented with a 3-month history of fever, night sweats, significant weight loss, bilateral peri-orbital haematoma, red eyes and retro-orbital headache. Physical examination revealed fever, bilateral peri-orbital haematoma, subconjunctival haemorrhage and palpable cervical lymphadenopathy. CT scans detected conical intra-orbital lesions, cervical adenomegalies, expansive lesions in the adrenal glands, and thrombosis of the splenomesenteric confluent and posterior segment of the right branch of the portal vein. These findings were suggestive of a lymphoproliferative disorder. Aspiration cytology of the adrenal mass and inguinal adenopathies was compatible with diffuse large B-cell lymphoma with areas of transformation to Burkitt’s lymphoma. We describe a rare form of lymphoma, and a very unusual presentation of primary intraocular lymphoma with atypical symptoms.https://www.ejcrim.com/index.php/EJCRIM/article/view/3622intraocular lymphomaocular haemorrhageadrenal mass
spellingShingle Catarina Pestana Santos
Rosa Alves
Bruno Sousa
Ana Cláudia Vieira
Tiago Judas
Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
European Journal of Case Reports in Internal Medicine
intraocular lymphoma
ocular haemorrhage
adrenal mass
title Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
title_full Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
title_fullStr Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
title_full_unstemmed Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
title_short Intraocular Lymphoma: When to Suspect a Sinister Cause of Ocular Haemorrhage
title_sort intraocular lymphoma when to suspect a sinister cause of ocular haemorrhage
topic intraocular lymphoma
ocular haemorrhage
adrenal mass
url https://www.ejcrim.com/index.php/EJCRIM/article/view/3622
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AT rosaalves intraocularlymphomawhentosuspectasinistercauseofocularhaemorrhage
AT brunosousa intraocularlymphomawhentosuspectasinistercauseofocularhaemorrhage
AT anaclaudiavieira intraocularlymphomawhentosuspectasinistercauseofocularhaemorrhage
AT tiagojudas intraocularlymphomawhentosuspectasinistercauseofocularhaemorrhage