| Summary: | <i>Salmonella enterica</i> subsp. <i>houtenae</i> (<i>S. houtenae</i>) is a common subspecies in reptiles and has been implicated as a source of serious and life-threatening diseases in humans. Although occurrence and significance of <i>S. houtenae</i> infections have been extensively studied, the genetic features of <i>S. houtenae</i> have remained unknown due to a lack of available high-quality genome sequences. We obtained the complete genome sequence of <i>S. houtenae</i> 45:g,z51:- strain 20-369 isolated from multiple abdominal abscesses of an African fat-tailed gecko (<i>Hemitheconyx caudicinctus</i>) using Nanopore and Illumina sequencing technologies and generated the 4.65Mbp complete genome sequence of the <i>S. houtenae</i> str. 20-369. We annotated and analyzed the genome sequence with the aim to gain a deeper understanding of the genome characteristics associated with its pathogenicity. Overall, this study found several interesting genomic features such as pseudogene formation, virulence gene profile, and novel genomic islands. This study provides basis for an understanding possible genetic mechanism underlying pathogenicity of <i>S. houtenae</i> 45:g,z51:- as well as a high-quality genome reference for future comparison studies.
|
|---|