Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin
Coronavirus disease 2019 (COVID-19) vaccinations have been associated with a higher risk of thromboembolic events. There have been no reports of central retinal artery occlusion (CRAO) after vaccination with the indigenously developed Covaxin, and worldwide, there has been only one such isolated cas...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3716;epage=3718;aulast=Thakar |
| _version_ | 1811239473655054336 |
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| author | Meenakshi Thakar Shruti Bhattacharya |
| author_facet | Meenakshi Thakar Shruti Bhattacharya |
| author_sort | Meenakshi Thakar |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) vaccinations have been associated with a higher risk of thromboembolic events. There have been no reports of central retinal artery occlusion (CRAO) after vaccination with the indigenously developed Covaxin, and worldwide, there has been only one such isolated case after administration of the AstraZeneca vaccine. We report a case of a 44-year-old healthy man who presented with sudden painless vision loss in his left eye 10 days after receiving Covaxin. His best-corrected visual acuity was minimal perception of light, with a relative afferent pupillary defect. Fundus examination revealed arterial attenuation and macular cherry red spot, suggesting an acute CRAO. Optical coherence tomography showed macular swelling and disorganization of the inner layers due to ischemic sequelae. Blood work was normal and cardiovascular examination was unremarkable. The patient was kept on follow-up. To our knowledge, this is the first case of an isolated CRAO after Covaxin administration, but further studies are needed to evaluate this potential association. |
| first_indexed | 2024-04-12T13:00:23Z |
| format | Article |
| id | doaj.art-9dc3ae9ddbc54d89b057b58d6ddb84f5 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-12T13:00:23Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-9dc3ae9ddbc54d89b057b58d6ddb84f52022-12-22T03:32:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170103716371810.4103/ijo.IJO_1148_22Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine CovaxinMeenakshi ThakarShruti BhattacharyaCoronavirus disease 2019 (COVID-19) vaccinations have been associated with a higher risk of thromboembolic events. There have been no reports of central retinal artery occlusion (CRAO) after vaccination with the indigenously developed Covaxin, and worldwide, there has been only one such isolated case after administration of the AstraZeneca vaccine. We report a case of a 44-year-old healthy man who presented with sudden painless vision loss in his left eye 10 days after receiving Covaxin. His best-corrected visual acuity was minimal perception of light, with a relative afferent pupillary defect. Fundus examination revealed arterial attenuation and macular cherry red spot, suggesting an acute CRAO. Optical coherence tomography showed macular swelling and disorganization of the inner layers due to ischemic sequelae. Blood work was normal and cardiovascular examination was unremarkable. The patient was kept on follow-up. To our knowledge, this is the first case of an isolated CRAO after Covaxin administration, but further studies are needed to evaluate this potential association.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3716;epage=3718;aulast=Thakarcovaxincovid vaccinationcrao |
| spellingShingle | Meenakshi Thakar Shruti Bhattacharya Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin Indian Journal of Ophthalmology covaxin covid vaccination crao |
| title | Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin |
| title_full | Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin |
| title_fullStr | Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin |
| title_full_unstemmed | Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin |
| title_short | Central retinal artery occlusion after vaccination with whole virion inactivated SARSCoV- 2 vaccine Covaxin |
| title_sort | central retinal artery occlusion after vaccination with whole virion inactivated sarscov 2 vaccine covaxin |
| topic | covaxin covid vaccination crao |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3716;epage=3718;aulast=Thakar |
| work_keys_str_mv | AT meenakshithakar centralretinalarteryocclusionaftervaccinationwithwholevirioninactivatedsarscov2vaccinecovaxin AT shrutibhattacharya centralretinalarteryocclusionaftervaccinationwithwholevirioninactivatedsarscov2vaccinecovaxin |