Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident
Exposure to ionizing radiation induces free radicals in human nails. These free radicals generate a radiation-induced signal (RIS) in electron paramagnetic resonance (EPR) spectroscopy. Compared with the RIS of tooth enamel samples, that in human nails is more affected by moisture and heat, but has...
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| Format: | Article |
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Elsevier
2023-01-01
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| Series: | Nuclear Engineering and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1738573322004132 |
| _version_ | 1797955432499642368 |
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| author | Jae Seok Kim Byeong Ryong Park Minsu Cho Won Il Jang Yong Kyun Kim |
| author_facet | Jae Seok Kim Byeong Ryong Park Minsu Cho Won Il Jang Yong Kyun Kim |
| author_sort | Jae Seok Kim |
| collection | DOAJ |
| description | Exposure to ionizing radiation induces free radicals in human nails. These free radicals generate a radiation-induced signal (RIS) in electron paramagnetic resonance (EPR) spectroscopy. Compared with the RIS of tooth enamel samples, that in human nails is more affected by moisture and heat, but has the advantages of being sensitive to radiation and easy to collect. The fingernail as a biological sample is applicable in retrospective dosimetry in cases of localized hand exposure accidents. In this study, the dosimetric characteristics of fingernails were analyzed in fingernail clippings collected from Korean donors. The dose response, fading of radiation-induced and mechanically induced signals, treatment method for evaluation of background signal, minimum detectable dose, and minimum detectable mass were investigated to propose a fingernail-EPR dosimetry protocol. In addition, to validate the practicality of the protocol, blind and field experiments were performed in the laboratory and a non-destructive testing facility. The relative biases in the dose assessment result of the blind and field experiments were 8.43% and 21.68% on average between the reference and reconstructed doses. The results of this study suggest that fingernail-EPR dosimetry can be a useful method for the application of retrospective dosimetry in cases of radiological accidents. |
| first_indexed | 2024-04-10T23:34:10Z |
| format | Article |
| id | doaj.art-9dc4b0d777c34e80845c4fbfa589e8b4 |
| institution | Directory Open Access Journal |
| issn | 1738-5733 |
| language | English |
| last_indexed | 2024-04-10T23:34:10Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Nuclear Engineering and Technology |
| spelling | doaj.art-9dc4b0d777c34e80845c4fbfa589e8b42023-01-12T04:18:37ZengElsevierNuclear Engineering and Technology1738-57332023-01-01551270277Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accidentJae Seok Kim0Byeong Ryong Park1Minsu Cho2Won Il Jang3Yong Kyun Kim4National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul, Republic of Korea; Department of Nuclear Engineering, University of Hanyang, 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of Korea; Corresponding author. 75, Nowon-ro Nowon-gu, Seoul 01812 Korea, Republic of Korea.National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul, Republic of KoreaNational Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul, Republic of KoreaNational Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul, Republic of KoreaDepartment of Nuclear Engineering, University of Hanyang, 222 Wangsimni-ro, Seongdong-gu, Seoul, Republic of KoreaExposure to ionizing radiation induces free radicals in human nails. These free radicals generate a radiation-induced signal (RIS) in electron paramagnetic resonance (EPR) spectroscopy. Compared with the RIS of tooth enamel samples, that in human nails is more affected by moisture and heat, but has the advantages of being sensitive to radiation and easy to collect. The fingernail as a biological sample is applicable in retrospective dosimetry in cases of localized hand exposure accidents. In this study, the dosimetric characteristics of fingernails were analyzed in fingernail clippings collected from Korean donors. The dose response, fading of radiation-induced and mechanically induced signals, treatment method for evaluation of background signal, minimum detectable dose, and minimum detectable mass were investigated to propose a fingernail-EPR dosimetry protocol. In addition, to validate the practicality of the protocol, blind and field experiments were performed in the laboratory and a non-destructive testing facility. The relative biases in the dose assessment result of the blind and field experiments were 8.43% and 21.68% on average between the reference and reconstructed doses. The results of this study suggest that fingernail-EPR dosimetry can be a useful method for the application of retrospective dosimetry in cases of radiological accidents.http://www.sciencedirect.com/science/article/pii/S1738573322004132Electron paramagnetic resonance (EPR) spectroscopyLocalized hand exposureFingernailDosimetric characteristics |
| spellingShingle | Jae Seok Kim Byeong Ryong Park Minsu Cho Won Il Jang Yong Kyun Kim Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident Nuclear Engineering and Technology Electron paramagnetic resonance (EPR) spectroscopy Localized hand exposure Fingernail Dosimetric characteristics |
| title | Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| title_full | Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| title_fullStr | Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| title_full_unstemmed | Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| title_short | Fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| title_sort | fingernail electron paramagnetic resonance dosimetry protocol for localized hand exposure accident |
| topic | Electron paramagnetic resonance (EPR) spectroscopy Localized hand exposure Fingernail Dosimetric characteristics |
| url | http://www.sciencedirect.com/science/article/pii/S1738573322004132 |
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