Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis
Infections with extensively drug-resistant Acinetobacter baumannii (XDRAB) have limited therapeutic options. We report successful salvage treatment of XDRAB and Pseudomonas aeruginosa-infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephrit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-08-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971221005245 |
| _version_ | 1818669297279434752 |
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| author | Kimberly Cipko Alice Kizny Gordon Suman Adhikari Pamela Konecny |
| author_facet | Kimberly Cipko Alice Kizny Gordon Suman Adhikari Pamela Konecny |
| author_sort | Kimberly Cipko |
| collection | DOAJ |
| description | Infections with extensively drug-resistant Acinetobacter baumannii (XDRAB) have limited therapeutic options. We report successful salvage treatment of XDRAB and Pseudomonas aeruginosa-infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephritis after 32 days of treatment. |
| first_indexed | 2024-12-17T06:49:58Z |
| format | Article |
| id | doaj.art-9dc77aba527c4e609d629adb7c14e3cb |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-17T06:49:58Z |
| publishDate | 2021-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-9dc77aba527c4e609d629adb7c14e3cb2022-12-21T21:59:38ZengElsevierInternational Journal of Infectious Diseases1201-97122021-08-01109108111Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritisKimberly Cipko0Alice Kizny Gordon1Suman Adhikari2Pamela Konecny3Department of Infectious Diseases, Immunology and Sexual Health, St George Hospital, Sydney, New South Wales, Australia; Graduate School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia; Corresponding author: Kimberly Cipko, Department of Infectious Diseases, Immunology and Sexual Health, St George Hospital, 2 South Street, Kogarah, New South Wales 2217, Australia. Tel: +61 2 9113 2955. Fax: +61 2 9113 3891.Department of Microbiology, New South Wales Health Pathology, St George Hospital, New South Wales, Australia; St George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, AustraliaSt George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia; Department of Pharmacy, St George Hospital, Sydney, New South Wales, AustraliaDepartment of Infectious Diseases, Immunology and Sexual Health, St George Hospital, Sydney, New South Wales, Australia; St George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, AustraliaInfections with extensively drug-resistant Acinetobacter baumannii (XDRAB) have limited therapeutic options. We report successful salvage treatment of XDRAB and Pseudomonas aeruginosa-infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephritis after 32 days of treatment.http://www.sciencedirect.com/science/article/pii/S1201971221005245Extensively drug-resistant Acinetobacter baumannii (XDRAB)CefiderocolMDR Gram-negativeSpinal hardware infectionBiofilmAcute interstitial nephritis |
| spellingShingle | Kimberly Cipko Alice Kizny Gordon Suman Adhikari Pamela Konecny Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis International Journal of Infectious Diseases Extensively drug-resistant Acinetobacter baumannii (XDRAB) Cefiderocol MDR Gram-negative Spinal hardware infection Biofilm Acute interstitial nephritis |
| title | Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| title_full | Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| title_fullStr | Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| title_full_unstemmed | Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| title_short | Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| title_sort | cefiderocol treatment of pseudomonas aeruginosa and extensively drug resistant acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis |
| topic | Extensively drug-resistant Acinetobacter baumannii (XDRAB) Cefiderocol MDR Gram-negative Spinal hardware infection Biofilm Acute interstitial nephritis |
| url | http://www.sciencedirect.com/science/article/pii/S1201971221005245 |
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