CT manifestations and differentiation of thymic squamous cell carcinoma
<b>Objective</b> To explore the CT imaging features and differentiation of thymic squamous cell carcinoma to improve the recognition and diagnosis level of it. <b>Methods</b> Of 39 patients with thymic tumor confirmed by surgery or puncture pathology from June 2014 to June 2...
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| Format: | Article |
| Language: | zho |
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The Editorial Department of Chinese Journal of Clinical Research
2022-12-01
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| Series: | Zhongguo linchuang yanjiu |
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| Online Access: | http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221213&flag=1 |
| _version_ | 1828067247761915904 |
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| author | LU Li-jun GUO Jian-wei ZHANG Ming |
| author_facet | LU Li-jun GUO Jian-wei ZHANG Ming |
| author_sort | LU Li-jun |
| collection | DOAJ |
| description | <b>Objective</b> To explore the CT imaging features and differentiation of thymic squamous cell carcinoma to improve the recognition and diagnosis level of it. <b>Methods</b> Of 39 patients with thymic tumor confirmed by surgery or puncture pathology from June 2014 to June 2021 in Sengong Hospital of Shannxi Province, 25 patients with thymic squamous cell carcinoma were collected as observation group and 14 patients with high-risk thymoma were served as control group. The clinical manifestations, Masaoka staging and CT signs were summarized and compared between two groups. <b>Results</b> The Masaoka staging system showed that most of thymic squamous cell carcinoma were stage Ⅲ(28.0%, 7/25) and stage Ⅳ(52.0%, 13/25) in observation group, which were significantly different from those in control group( <i>χ</i><sup>2</sup>=9.762, <i>P</i>=0.021). The incidences of lobulated tumor, blurred boundaries, pericardial invasion, mediastinal fat infiltration in observation group were statistical higher than those in control group(<i>P</i>＜0.05). There was no significant difference in tumor internal partition, density, degree of enhancement, calcification and cystic, perfusion type growth, invasion of large vessels, pleural invasion, lymph node metastasis, pulmonary metastasis and pleural implantation between two groups(<i>P</i>＞0.05). <b>Conclusion</b> There is no obvious specificity in the clinical manifestations of thymic squamous cell carcinoma. CT manifestations are mostly characterized by anterior middle and upper mediastinal lobular mass with blurred boundaries and perfusion growth along macrovascular shape in some of them. The tumor is highly invasive to surrounding tissues and can invade macrovascular, pleura and pericardium. Mediastinal fat infiltration are common, and Masaoka staging is mostly stage Ⅲ and Ⅳ.
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| first_indexed | 2024-04-10T23:42:51Z |
| format | Article |
| id | doaj.art-9dca1bbb1710465ca5688f09e46b4f13 |
| institution | Directory Open Access Journal |
| issn | 1674-8182 |
| language | zho |
| last_indexed | 2024-04-10T23:42:51Z |
| publishDate | 2022-12-01 |
| publisher | The Editorial Department of Chinese Journal of Clinical Research |
| record_format | Article |
| series | Zhongguo linchuang yanjiu |
| spelling | doaj.art-9dca1bbb1710465ca5688f09e46b4f132023-01-11T06:00:22ZzhoThe Editorial Department of Chinese Journal of Clinical ResearchZhongguo linchuang yanjiu1674-81822022-12-0135121693169810.13429/j.cnki.cjcr.2022.12.013CT manifestations and differentiation of thymic squamous cell carcinomaLU Li-jun0GUO Jian-wei1ZHANG Ming2School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, ChinaCT Room of Shaanxi Provincial Forest Industry Staff Hospital, Xi'an, Shaanxi 710300, ChinaSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, China<b>Objective</b> To explore the CT imaging features and differentiation of thymic squamous cell carcinoma to improve the recognition and diagnosis level of it. <b>Methods</b> Of 39 patients with thymic tumor confirmed by surgery or puncture pathology from June 2014 to June 2021 in Sengong Hospital of Shannxi Province, 25 patients with thymic squamous cell carcinoma were collected as observation group and 14 patients with high-risk thymoma were served as control group. The clinical manifestations, Masaoka staging and CT signs were summarized and compared between two groups. <b>Results</b> The Masaoka staging system showed that most of thymic squamous cell carcinoma were stage Ⅲ(28.0%, 7/25) and stage Ⅳ(52.0%, 13/25) in observation group, which were significantly different from those in control group( <i>χ</i><sup>2</sup>=9.762, <i>P</i>=0.021). The incidences of lobulated tumor, blurred boundaries, pericardial invasion, mediastinal fat infiltration in observation group were statistical higher than those in control group(<i>P</i>＜0.05). There was no significant difference in tumor internal partition, density, degree of enhancement, calcification and cystic, perfusion type growth, invasion of large vessels, pleural invasion, lymph node metastasis, pulmonary metastasis and pleural implantation between two groups(<i>P</i>＞0.05). <b>Conclusion</b> There is no obvious specificity in the clinical manifestations of thymic squamous cell carcinoma. CT manifestations are mostly characterized by anterior middle and upper mediastinal lobular mass with blurred boundaries and perfusion growth along macrovascular shape in some of them. The tumor is highly invasive to surrounding tissues and can invade macrovascular, pleura and pericardium. Mediastinal fat infiltration are common, and Masaoka staging is mostly stage Ⅲ and Ⅳ. http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221213&flag=1thymus glandthymic epithelial tumorssquamous cell carcinomatomographyx-ray computed |
| spellingShingle | LU Li-jun GUO Jian-wei ZHANG Ming CT manifestations and differentiation of thymic squamous cell carcinoma Zhongguo linchuang yanjiu thymus gland thymic epithelial tumors squamous cell carcinoma tomography x-ray computed |
| title | CT manifestations and differentiation of thymic squamous cell carcinoma |
| title_full | CT manifestations and differentiation of thymic squamous cell carcinoma |
| title_fullStr | CT manifestations and differentiation of thymic squamous cell carcinoma |
| title_full_unstemmed | CT manifestations and differentiation of thymic squamous cell carcinoma |
| title_short | CT manifestations and differentiation of thymic squamous cell carcinoma |
| title_sort | ct manifestations and differentiation of thymic squamous cell carcinoma |
| topic | thymus gland thymic epithelial tumors squamous cell carcinoma tomography x-ray computed |
| url | http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221213&flag=1 |
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