The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia
The article concerns one of the common adverse effects during treatment — steroid myopathy. The information about pathogenic specifics of myopathy development in administration of glucocorticoids, the most typical clinical manifestations are described, and results diagnostic methods with estimation...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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SINAPS LLC
2020-07-01
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| Series: | Архивъ внутренней медицины |
| Subjects: | |
| Online Access: | https://www.medarhive.ru/jour/article/view/1077 |
| _version_ | 1826558726869352448 |
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| author | N. T. Vatutin G. A. Ignatenko G. G. Taradin I. V. Kanisheva M. R. Shajmurzin |
| author_facet | N. T. Vatutin G. A. Ignatenko G. G. Taradin I. V. Kanisheva M. R. Shajmurzin |
| author_sort | N. T. Vatutin |
| collection | DOAJ |
| description | The article concerns one of the common adverse effects during treatment — steroid myopathy. The information about pathogenic specifics of myopathy development in administration of glucocorticoids, the most typical clinical manifestations are described, and results diagnostic methods with estimation of a role of enzyme level evaluation, electromyography, ultrasound study of the muscle tissue, computer and magnetic resonance tomography. There is description of muscle weakness development in 49-year old woman who has been receiving methylprednisolone 88 mg/day due to revealed thrombocytopenia. One week after the treatment was started the patient experienced onset and progression of muscle weakness limiting her motion and self-maintenance. After performing of investigation including electromyography steroid genesis of myopathy was suggested. The patient’s condition began to improve after disc ontinuation of glucocorticoids and administration of calcium supplements, vitamin D, and anabolics, and the patient was discharged. |
| first_indexed | 2024-04-10T03:56:19Z |
| format | Article |
| id | doaj.art-9dce57c0ff23492290fd45e2b44983cf |
| institution | Directory Open Access Journal |
| issn | 2226-6704 2411-6564 |
| language | Russian |
| last_indexed | 2025-03-14T08:49:05Z |
| publishDate | 2020-07-01 |
| publisher | SINAPS LLC |
| record_format | Article |
| series | Архивъ внутренней медицины |
| spelling | doaj.art-9dce57c0ff23492290fd45e2b44983cf2025-03-02T12:49:01ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642020-07-0110431432110.20514/2226-6704-2020-10-4-314-321805The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune ThrombocytopeniaN. T. Vatutin0G. A. Ignatenko1G. G. Taradin2I. V. Kanisheva3M. R. Shajmurzin4State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»; State Institution «V.K. Gusak Institute of Urgent and Recovery Surgery»State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»; State Institution «V.K. Gusak Institute of Urgent and Recovery Surgery»State Educational Organization of Higher Professional Education «M. Gorky Donetsk National Medical University»Hospital of Republican Clinical Centre for NeurorehabilitationThe article concerns one of the common adverse effects during treatment — steroid myopathy. The information about pathogenic specifics of myopathy development in administration of glucocorticoids, the most typical clinical manifestations are described, and results diagnostic methods with estimation of a role of enzyme level evaluation, electromyography, ultrasound study of the muscle tissue, computer and magnetic resonance tomography. There is description of muscle weakness development in 49-year old woman who has been receiving methylprednisolone 88 mg/day due to revealed thrombocytopenia. One week after the treatment was started the patient experienced onset and progression of muscle weakness limiting her motion and self-maintenance. After performing of investigation including electromyography steroid genesis of myopathy was suggested. The patient’s condition began to improve after disc ontinuation of glucocorticoids and administration of calcium supplements, vitamin D, and anabolics, and the patient was discharged.https://www.medarhive.ru/jour/article/view/1077thrombocytopeniamethylprednisoloneglucocorticoidsadverse effectssteroid myopathytreatment |
| spellingShingle | N. T. Vatutin G. A. Ignatenko G. G. Taradin I. V. Kanisheva M. R. Shajmurzin The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia Архивъ внутренней медицины thrombocytopenia methylprednisolone glucocorticoids adverse effects steroid myopathy treatment |
| title | The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia |
| title_full | The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia |
| title_fullStr | The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia |
| title_full_unstemmed | The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia |
| title_short | The Case of Acute Steroid-Induced Myopathy in the Patient with Autoimmune Thrombocytopenia |
| title_sort | case of acute steroid induced myopathy in the patient with autoimmune thrombocytopenia |
| topic | thrombocytopenia methylprednisolone glucocorticoids adverse effects steroid myopathy treatment |
| url | https://www.medarhive.ru/jour/article/view/1077 |
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