Clinical and genetic characterization of hereditary breast cancer in a Chinese population

Clinical and genetic characterization of hereditary breast cancer in a Chinese population

Abstract Background Breast cancer develops as a result of multiple gene mutations in combination with environmental risk factors. Causative variants in genes such as BRCA1 and/or BRCA2 have been shown to account for hereditary nature of certain breast cancers. However,other genes, such as ATM, PALB2...

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Bibliographic Details
Main Authors: Wenjing Jian, Kang Shao, Qi Qin, Xiaohong Wang, Shufen Song, Xianming Wang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Hereditary breast cancer
Causative variant
Gene panel
NGS
Online Access:http://link.springer.com/article/10.1186/s13053-017-0079-4

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