Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation

Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation

BackgroundNeuroinflammation is an important factor causing numerous neurodegenerative pathologies. Inflammation can lead to abnormal neuronal structure and function and even death, followed by cognitive dysfunction. There is growing evidence that chlorogenic acid has anti-inflammatory effects and im...

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Bibliographic Details
Main Authors: Siyuan Xiong, Xuyang Su, Yingjie Kang, Junqiang Si, Lu Wang, Xinzhi Li, Ketao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
chlorogenic acid
neuroinflammation
cognitive dysfunction
microglia
polarization
TNF signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178188/full

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