Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial

Background. The optimal combination of chemotherapy with radiation therapy for treatment locally advanced non-small cell lung cancer (NSCLC) remains an open issue. This randomized phase II study compared gemcitabine in two different schedules and cisplatin - as induction chemotherapy, followed by ra...

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Main Authors: Vrankar Martina, Zwitter Matjaz, Bavcar Tanja, Milic Ana, Kovac Viljem
Format: Article
Language:English
Published: Sciendo 2014-12-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2014-0026
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author Vrankar Martina
Zwitter Matjaz
Bavcar Tanja
Milic Ana
Kovac Viljem
author_facet Vrankar Martina
Zwitter Matjaz
Bavcar Tanja
Milic Ana
Kovac Viljem
author_sort Vrankar Martina
collection DOAJ
description Background. The optimal combination of chemotherapy with radiation therapy for treatment locally advanced non-small cell lung cancer (NSCLC) remains an open issue. This randomized phase II study compared gemcitabine in two different schedules and cisplatin - as induction chemotherapy, followed by radiation therapy concurrent with cisplatin and etoposid.
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spelling doaj.art-9dd733feefa743f59f11d097d9dcdf772022-12-21T22:00:42ZengSciendoRadiology and Oncology1581-32072014-12-0148436938010.2478/raon-2014-0026raon-2014-0026Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trialVrankar Martina0Zwitter Matjaz1Bavcar Tanja2Milic Ana3Kovac Viljem4Institute of Oncology Ljubljana, Ljubljana, SloveniaInstitute of Oncology Ljubljana, Ljubljana, Slovenia / Faculty of Medicine, University of Maribor, SloveniaClinical Radiology Institute, University Medical Centre Ljubljana, SloveniaInstitute of Oncology Ljubljana, Ljubljana, SloveniaInstitute of Oncology Ljubljana, Ljubljana, SloveniaBackground. The optimal combination of chemotherapy with radiation therapy for treatment locally advanced non-small cell lung cancer (NSCLC) remains an open issue. This randomized phase II study compared gemcitabine in two different schedules and cisplatin - as induction chemotherapy, followed by radiation therapy concurrent with cisplatin and etoposid.https://doi.org/10.2478/raon-2014-0026induction chemotherapygemcitabinenon-small cell lung cancerradiation therapyconcurrent chemoradiationrandomized clinical trial
spellingShingle Vrankar Martina
Zwitter Matjaz
Bavcar Tanja
Milic Ana
Kovac Viljem
Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
Radiology and Oncology
induction chemotherapy
gemcitabine
non-small cell lung cancer
radiation therapy
concurrent chemoradiation
randomized clinical trial
title Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
title_full Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
title_fullStr Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
title_full_unstemmed Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
title_short Induction gemcitabine in standard dose or prolonged low-dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non-small cell lung cancer: a randomized phase II clinical trial
title_sort induction gemcitabine in standard dose or prolonged low dose with cisplatin followed by concurrent radiochemotherapy in locally advanced non small cell lung cancer a randomized phase ii clinical trial
topic induction chemotherapy
gemcitabine
non-small cell lung cancer
radiation therapy
concurrent chemoradiation
randomized clinical trial
url https://doi.org/10.2478/raon-2014-0026
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