Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
The Na+-pumping NADH-ubiquinone oxidoreductase (Na+-NQR) is a unique respiratory enzyme found in many pathogenic bacteria. Here, the authors present high-resolution cryo-EM structures of Na+-NQR from V. cholerae with or without a bound inhibitor.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31718-1 |
| _version_ | 1818163011645341696 |
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| author | Jun-ichi Kishikawa Moe Ishikawa Takahiro Masuya Masatoshi Murai Yuki Kitazumi Nicole L. Butler Takayuki Kato Blanca Barquera Hideto Miyoshi |
| author_facet | Jun-ichi Kishikawa Moe Ishikawa Takahiro Masuya Masatoshi Murai Yuki Kitazumi Nicole L. Butler Takayuki Kato Blanca Barquera Hideto Miyoshi |
| author_sort | Jun-ichi Kishikawa |
| collection | DOAJ |
| description | The Na+-pumping NADH-ubiquinone oxidoreductase (Na+-NQR) is a unique respiratory enzyme found in many pathogenic bacteria. Here, the authors present high-resolution cryo-EM structures of Na+-NQR from V. cholerae with or without a bound inhibitor. |
| first_indexed | 2024-12-11T16:42:47Z |
| format | Article |
| id | doaj.art-9ddb4f055cc94baea25575c6856ebbc2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-11T16:42:47Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9ddb4f055cc94baea25575c6856ebbc22022-12-22T00:58:18ZengNature PortfolioNature Communications2041-17232022-07-0113111110.1038/s41467-022-31718-1Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio choleraeJun-ichi Kishikawa0Moe Ishikawa1Takahiro Masuya2Masatoshi Murai3Yuki Kitazumi4Nicole L. Butler5Takayuki Kato6Blanca Barquera7Hideto Miyoshi8Institute for Protein Research, Osaka UniversityDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto UniversityDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto UniversityDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto UniversityDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto UniversityDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic InstituteInstitute for Protein Research, Osaka UniversityDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic InstituteDivision of Applied Life Sciences, Graduate School of Agriculture, Kyoto UniversityThe Na+-pumping NADH-ubiquinone oxidoreductase (Na+-NQR) is a unique respiratory enzyme found in many pathogenic bacteria. Here, the authors present high-resolution cryo-EM structures of Na+-NQR from V. cholerae with or without a bound inhibitor.https://doi.org/10.1038/s41467-022-31718-1 |
| spellingShingle | Jun-ichi Kishikawa Moe Ishikawa Takahiro Masuya Masatoshi Murai Yuki Kitazumi Nicole L. Butler Takayuki Kato Blanca Barquera Hideto Miyoshi Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae Nature Communications |
| title | Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae |
| title_full | Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae |
| title_fullStr | Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae |
| title_full_unstemmed | Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae |
| title_short | Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae |
| title_sort | cryo em structures of na pumping nadh ubiquinone oxidoreductase from vibrio cholerae |
| url | https://doi.org/10.1038/s41467-022-31718-1 |
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