Epilepsy lifetime prevalence in Iran: a large population- based national survey
Abstract Epilepsy has garnered increased public health focus because patients who suffer from epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment and care advances. The epidemiology of epilepsy is diverse in different countries and regions. This natio...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-89048-z |
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| author | Hossein Pakdaman Ali Amini Harandi Koroush Gharagozli Farshid Alaeddini Akram Esfandani Seyed Hamidreza Mirbehbahani Taher Doroudi Pirhossein Kolivand Parviz Bahrami Hadi Kazemi |
| author_facet | Hossein Pakdaman Ali Amini Harandi Koroush Gharagozli Farshid Alaeddini Akram Esfandani Seyed Hamidreza Mirbehbahani Taher Doroudi Pirhossein Kolivand Parviz Bahrami Hadi Kazemi |
| author_sort | Hossein Pakdaman |
| collection | DOAJ |
| description | Abstract Epilepsy has garnered increased public health focus because patients who suffer from epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment and care advances. The epidemiology of epilepsy is diverse in different countries and regions. This nationwide population-based cross-sectional study was conducted to determine the life time prevalence and health related factors of epilepsy for the first time in Iran through a two-phase door-to-door survey method. In phase I, a screening for epilepsy was performed on 68,035 people. Then in phase II, after the neurological evaluation of participants and reviewing medical records, 1130 subjects with epilepsy was confirmed. The life time prevalence of epilepsy was achieved to be 16.6 per 1000 people (95% CI 15.4–17.8) with the average age onset 19.1 ± 21.1 (active prevalence 9.5 per 1000 people). Focal seizure (59.3%), generalized epilepsy (38%) and unknown types of epilepsy (2.7%) were detected among participants. The overall life time prevalence of febrile convulsion was 4.1 per 1000 people. The frequency of attacks per year and per month were 3.0 ± 1.6 and 0.5 ± 0.1, respectively. Age-specific life time prevalence was highest among the age group of 15–19 years old [32.7 per 1000 persons (95% CI 29.1–36.8)] and it was higher in male (53.8%) than female (46.2%) participants. Our results showed that the life time prevalence of epilepsy in Iran is higher than worldwide average. |
| first_indexed | 2024-12-21T09:36:16Z |
| format | Article |
| id | doaj.art-9ddb771057bb4126859a047085d440bf |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T09:36:16Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-9ddb771057bb4126859a047085d440bf2022-12-21T19:08:38ZengNature PortfolioScientific Reports2045-23222021-05-011111910.1038/s41598-021-89048-zEpilepsy lifetime prevalence in Iran: a large population- based national surveyHossein Pakdaman0Ali Amini Harandi1Koroush Gharagozli2Farshid Alaeddini3Akram Esfandani4Seyed Hamidreza Mirbehbahani5Taher Doroudi6Pirhossein Kolivand7Parviz Bahrami8Hadi Kazemi9Brain Mapping Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesShefa Neuroscience Research Center, Khatam-Ol-Anbia HospitalShefa Neuroscience Research Center, Khatam-Ol-Anbia HospitalShefa Neuroscience Research Center, Khatam-Ol-Anbia HospitalShefa Neuroscience Research Center, Khatam-Ol-Anbia HospitalAbstract Epilepsy has garnered increased public health focus because patients who suffer from epilepsy experience pronounced and persistent health and socioeconomic disparities despite treatment and care advances. The epidemiology of epilepsy is diverse in different countries and regions. This nationwide population-based cross-sectional study was conducted to determine the life time prevalence and health related factors of epilepsy for the first time in Iran through a two-phase door-to-door survey method. In phase I, a screening for epilepsy was performed on 68,035 people. Then in phase II, after the neurological evaluation of participants and reviewing medical records, 1130 subjects with epilepsy was confirmed. The life time prevalence of epilepsy was achieved to be 16.6 per 1000 people (95% CI 15.4–17.8) with the average age onset 19.1 ± 21.1 (active prevalence 9.5 per 1000 people). Focal seizure (59.3%), generalized epilepsy (38%) and unknown types of epilepsy (2.7%) were detected among participants. The overall life time prevalence of febrile convulsion was 4.1 per 1000 people. The frequency of attacks per year and per month were 3.0 ± 1.6 and 0.5 ± 0.1, respectively. Age-specific life time prevalence was highest among the age group of 15–19 years old [32.7 per 1000 persons (95% CI 29.1–36.8)] and it was higher in male (53.8%) than female (46.2%) participants. Our results showed that the life time prevalence of epilepsy in Iran is higher than worldwide average.https://doi.org/10.1038/s41598-021-89048-z |
| spellingShingle | Hossein Pakdaman Ali Amini Harandi Koroush Gharagozli Farshid Alaeddini Akram Esfandani Seyed Hamidreza Mirbehbahani Taher Doroudi Pirhossein Kolivand Parviz Bahrami Hadi Kazemi Epilepsy lifetime prevalence in Iran: a large population- based national survey Scientific Reports |
| title | Epilepsy lifetime prevalence in Iran: a large population- based national survey |
| title_full | Epilepsy lifetime prevalence in Iran: a large population- based national survey |
| title_fullStr | Epilepsy lifetime prevalence in Iran: a large population- based national survey |
| title_full_unstemmed | Epilepsy lifetime prevalence in Iran: a large population- based national survey |
| title_short | Epilepsy lifetime prevalence in Iran: a large population- based national survey |
| title_sort | epilepsy lifetime prevalence in iran a large population based national survey |
| url | https://doi.org/10.1038/s41598-021-89048-z |
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