The Value of Targeting Complement Components in Asthma

Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target comp...

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Bibliographic Details
Main Authors: Marwa M. E. Mohamed, Alicia D. Nicklin, Cordula M. Stover
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/56/8/405
Description
Summary:Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target complement in this complex hypersensitivity reaction that develops chronicity and has a personal—as well as a societal—cost.
ISSN:1010-660X