On the clinical significance of cutaneous melanoma′s precursors

We can identify three main groups of cutaneous pigmented lesions that could be represented as melanoma precursors: (a) congenital melanocytic nevi, (b) dysplastic or atypical nevi, and (c) acquired melanocytic nevi. The occurrence of melanoma in small and intermediate congenital melanocytic nevi is...

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Main Author: Giuseppe Noto
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Indian Dermatology Online Journal
Subjects:
Online Access:http://www.idoj.in/article.asp?issn=2229-5178;year=2012;volume=3;issue=2;spage=83;epage=88;aulast=Noto
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author Giuseppe Noto
author_facet Giuseppe Noto
author_sort Giuseppe Noto
collection DOAJ
description We can identify three main groups of cutaneous pigmented lesions that could be represented as melanoma precursors: (a) congenital melanocytic nevi, (b) dysplastic or atypical nevi, and (c) acquired melanocytic nevi. The occurrence of melanoma in small and intermediate congenital melanocytic nevi is very uncommon, but there is a high risk in large congenital melanocytic nevi, in particular those arising in the so-called "bathing trunk" distribution. It is very important to distinguish the familial dysplastic nevus syndrome, which is a strong risk factor for cutaneous melanoma, from not familial (sporadic) dysplastic nevus, in which the risk for melanoma would depend on the total number of melanocytic nevi, phototype, and on the relationship to environmental factors.
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spelling doaj.art-9de073d6afa44b399b6adbe7a072bd552022-12-21T19:39:03ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782012-01-0132838810.4103/2229-5178.96690On the clinical significance of cutaneous melanoma′s precursorsGiuseppe NotoWe can identify three main groups of cutaneous pigmented lesions that could be represented as melanoma precursors: (a) congenital melanocytic nevi, (b) dysplastic or atypical nevi, and (c) acquired melanocytic nevi. The occurrence of melanoma in small and intermediate congenital melanocytic nevi is very uncommon, but there is a high risk in large congenital melanocytic nevi, in particular those arising in the so-called "bathing trunk" distribution. It is very important to distinguish the familial dysplastic nevus syndrome, which is a strong risk factor for cutaneous melanoma, from not familial (sporadic) dysplastic nevus, in which the risk for melanoma would depend on the total number of melanocytic nevi, phototype, and on the relationship to environmental factors.http://www.idoj.in/article.asp?issn=2229-5178;year=2012;volume=3;issue=2;spage=83;epage=88;aulast=NotoCongenital nevusdysplastic nevusmelanoma
spellingShingle Giuseppe Noto
On the clinical significance of cutaneous melanoma′s precursors
Indian Dermatology Online Journal
Congenital nevus
dysplastic nevus
melanoma
title On the clinical significance of cutaneous melanoma′s precursors
title_full On the clinical significance of cutaneous melanoma′s precursors
title_fullStr On the clinical significance of cutaneous melanoma′s precursors
title_full_unstemmed On the clinical significance of cutaneous melanoma′s precursors
title_short On the clinical significance of cutaneous melanoma′s precursors
title_sort on the clinical significance of cutaneous melanoma s precursors
topic Congenital nevus
dysplastic nevus
melanoma
url http://www.idoj.in/article.asp?issn=2229-5178;year=2012;volume=3;issue=2;spage=83;epage=88;aulast=Noto
work_keys_str_mv AT giuseppenoto ontheclinicalsignificanceofcutaneousmelanomasprecursors