Catch the rainbow: Prognostic factor of sarcoidosis

Sarcoidosis is a systemic, chronic, inflammatory disease characterized by noncaseating granuloma formations. The fact that the etiopathogenesis of the disease has not been elucidated yet brings it many theories and assumptions. Being a systemic disease and ability to involve many organs and systems,...

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Main Author: Senol Kobak
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Lung India
Subjects:
Online Access:http://www.lungindia.com/article.asp?issn=0970-2113;year=2020;volume=37;issue=5;spage=425;epage=432;aulast=Kobak
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author Senol Kobak
author_facet Senol Kobak
author_sort Senol Kobak
collection DOAJ
description Sarcoidosis is a systemic, chronic, inflammatory disease characterized by noncaseating granuloma formations. The fact that the etiopathogenesis of the disease has not been elucidated yet brings it many theories and assumptions. Being a systemic disease and ability to involve many organs and systems, it attracts the attention of physicians from different branches. In addition to lung involvement, skin, eye, heart, and locomotor system involvement is an important clinical finding. Sarcoidosis may present with very different clinical presentations, and therefore, it is one of the important “imitators” in the medical literature. I like sarcoidosis as a “rainbow,” it is a disease that contains the characteristics of many diseases. Different clinical, radiological, and laboratory prognostic factors (lupus pernio, chronic uveitis, late-onset disease, chronic hypercalcemia, nephrocalcinosis, Afro-American race, progressive pulmonary sarcoidosis, radiologic Stage 4, bone involvement, neurosarcoidosis, cardiac involvement, and chronic respiratory failure) have been defined in this “rainbow.” Early identification of these factors plays an important role in the determination of treatment strategies, morbidity, and mortality of the disease. In this article, clinical, genetic, laboratory, and radiological factors that determine the prognosis of sarcoidosis are discussed in light of the latest data in the literature.
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spelling doaj.art-9de0bcb89efe42e1bd268942586238672022-12-22T02:24:54ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2020-01-0137542543210.4103/lungindia.lungindia_380_19Catch the rainbow: Prognostic factor of sarcoidosisSenol KobakSarcoidosis is a systemic, chronic, inflammatory disease characterized by noncaseating granuloma formations. The fact that the etiopathogenesis of the disease has not been elucidated yet brings it many theories and assumptions. Being a systemic disease and ability to involve many organs and systems, it attracts the attention of physicians from different branches. In addition to lung involvement, skin, eye, heart, and locomotor system involvement is an important clinical finding. Sarcoidosis may present with very different clinical presentations, and therefore, it is one of the important “imitators” in the medical literature. I like sarcoidosis as a “rainbow,” it is a disease that contains the characteristics of many diseases. Different clinical, radiological, and laboratory prognostic factors (lupus pernio, chronic uveitis, late-onset disease, chronic hypercalcemia, nephrocalcinosis, Afro-American race, progressive pulmonary sarcoidosis, radiologic Stage 4, bone involvement, neurosarcoidosis, cardiac involvement, and chronic respiratory failure) have been defined in this “rainbow.” Early identification of these factors plays an important role in the determination of treatment strategies, morbidity, and mortality of the disease. In this article, clinical, genetic, laboratory, and radiological factors that determine the prognosis of sarcoidosis are discussed in light of the latest data in the literature.http://www.lungindia.com/article.asp?issn=0970-2113;year=2020;volume=37;issue=5;spage=425;epage=432;aulast=Kobakfactorsprognosissarcoidosis
spellingShingle Senol Kobak
Catch the rainbow: Prognostic factor of sarcoidosis
Lung India
factors
prognosis
sarcoidosis
title Catch the rainbow: Prognostic factor of sarcoidosis
title_full Catch the rainbow: Prognostic factor of sarcoidosis
title_fullStr Catch the rainbow: Prognostic factor of sarcoidosis
title_full_unstemmed Catch the rainbow: Prognostic factor of sarcoidosis
title_short Catch the rainbow: Prognostic factor of sarcoidosis
title_sort catch the rainbow prognostic factor of sarcoidosis
topic factors
prognosis
sarcoidosis
url http://www.lungindia.com/article.asp?issn=0970-2113;year=2020;volume=37;issue=5;spage=425;epage=432;aulast=Kobak
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