Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa
Background and Objective: Ferula gummosa Boiss. (Barije.) contain medical and antimicrobial properties. This study was done to determine the effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa. Materials and Methods: In this laboratory s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2013-11-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-696&slc_lang=en&sid=1 |
| _version_ | 1811276103634911232 |
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| author | Salehi M Hashemi Karuie SM Nasrolahi Omran A Mobini M Asghar Hedari M |
| author_facet | Salehi M Hashemi Karuie SM Nasrolahi Omran A Mobini M Asghar Hedari M |
| author_sort | Salehi M |
| collection | DOAJ |
| description | Background and Objective: Ferula gummosa Boiss. (Barije.) contain medical and antimicrobial properties. This study was done to determine the effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa. Materials and Methods: In this laboratory study, the plant was dried in dark place and aqueous, alcoholic extracts of Barije's root, powder were prepared using Soxhlet method. The efficacy of 0.1 dilution of different values of extracts of Ferula gummosa Boiss. on the strain of Pseudomonas aeruginosa (PTCC 1430) were evaluated by disk diffusion, Agar-well diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods. Results: Pseudomonas aeruginosa was completely resistant to the aqueous extract, and the MIC for the methanol and ethanol extracts was 1.25×104 μg/ml and 6.25×103 μg/ml, respectively. Conclusion: Methanolic and ethanolic extracts of Ferula gummosa Boiss. have antimicrobial activity against Pseudomonas aeruginosa in in-vitro model. |
| first_indexed | 2024-04-12T23:50:26Z |
| format | Article |
| id | doaj.art-9de12d247dc8439591c615b42e0bcf74 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-04-12T23:50:26Z |
| publishDate | 2013-11-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-9de12d247dc8439591c615b42e0bcf742022-12-22T03:11:43ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802013-11-011541822Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosaSalehi M0Hashemi Karuie SM1Nasrolahi Omran A2Mobini M3Asghar Hedari M4 MSc in Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran Assistant Professor, Department of Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran Assistant Professor, Department of Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran MSc in Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran MSc in Biology, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran Background and Objective: Ferula gummosa Boiss. (Barije.) contain medical and antimicrobial properties. This study was done to determine the effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa. Materials and Methods: In this laboratory study, the plant was dried in dark place and aqueous, alcoholic extracts of Barije's root, powder were prepared using Soxhlet method. The efficacy of 0.1 dilution of different values of extracts of Ferula gummosa Boiss. on the strain of Pseudomonas aeruginosa (PTCC 1430) were evaluated by disk diffusion, Agar-well diffusion, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods. Results: Pseudomonas aeruginosa was completely resistant to the aqueous extract, and the MIC for the methanol and ethanol extracts was 1.25×104 μg/ml and 6.25×103 μg/ml, respectively. Conclusion: Methanolic and ethanolic extracts of Ferula gummosa Boiss. have antimicrobial activity against Pseudomonas aeruginosa in in-vitro model.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-696&slc_lang=en&sid=1Ferula gummosa BoissPseudomonas aeruginosaMICMBC |
| spellingShingle | Salehi M Hashemi Karuie SM Nasrolahi Omran A Mobini M Asghar Hedari M Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa مجله دانشگاه علوم پزشکی گرگان Ferula gummosa Boiss Pseudomonas aeruginosa MIC MBC |
| title | Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa |
| title_full | Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa |
| title_fullStr | Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa |
| title_full_unstemmed | Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa |
| title_short | Effect of aqueous and alcoholic extracts of roots of Ferula gummosa Boiss. on the growth of Pseudomonas aeruginosa |
| title_sort | effect of aqueous and alcoholic extracts of roots of ferula gummosa boiss on the growth of pseudomonas aeruginosa |
| topic | Ferula gummosa Boiss Pseudomonas aeruginosa MIC MBC |
| url | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-696&slc_lang=en&sid=1 |
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