Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients
Background Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening program at a tertiary hospital in Korea....
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| Format: | Article |
| Language: | English |
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The Korean Academy of Tuberculosis and Respiratory Diseases
2018-04-01
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| Series: | Tuberculosis and Respiratory Diseases |
| Subjects: | |
| Online Access: | https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0039&code=0003TRD&vmode=FULL |
| _version_ | 1818065414856376320 |
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| author | Tae Yun Park, M.D. Jae-Woo Jung, M.D., Ph.D. Ju Young Jang, M.D., Ph.D. Jae Chol Choi, M.D., Ph.D. Jong Wook Shin, M.D., Ph.D., In Won Park, M.D., Ph.D. Byoung Whui Choi, M.D., Ph.D. Jae Yeol Kim, M.D., Ph.D. |
| author_facet | Tae Yun Park, M.D. Jae-Woo Jung, M.D., Ph.D. Ju Young Jang, M.D., Ph.D. Jae Chol Choi, M.D., Ph.D. Jong Wook Shin, M.D., Ph.D., In Won Park, M.D., Ph.D. Byoung Whui Choi, M.D., Ph.D. Jae Yeol Kim, M.D., Ph.D. |
| author_sort | Tae Yun Park, M.D. |
| collection | DOAJ |
| description | Background
Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening program at a tertiary hospital in Korea.
Methods
Data of private health screening program recipients at the health promotion center of Chung-Ang University Hospital from 2004 to 2013 were collected. Health-related questionnaires and laboratory findings of private health screening program with possible relation with eosinophilia were reviewed. Results of enzyme-linked immunosorbent assay (ELISA) for parasite, chest computed tomography, and pulmonary function test were also reviewed.
Results
The cumulative prevalence of eosinophilia was 4.0% (1,963 of 48,928). Prevalence of eosinophilia showed a decreased trend from 2004 to 2013. Most cases (96.6%) had mild degree of eosinophilia. Eosinophilic subjects were older and male-predominant. They showed lower levels of forced expiratory volume in 1 second (FEV1%), forced vital capacity (FVC%), and FEV1/FVC than those without eosinophilia. Eosinophilic subjects showed higher positive rate for common parasite in ELISA than those without eosinophilia. On radiologic findings, consolidation and ground glass opacities were positively associated with the degree of eosinophilia. When eosinophil was classified based on severity, statistically significant correlation between the severity of eosinophil and radiologic abnormalities was found.
Conclusion
Eosinophilia is uncommon in healthy population. It usually occurs at a mild degree. Eosinophilic patients have more radiologic abnormalities compared to those without eosinophilia. Such radiologic abnormalities are associated with the severity of eosinophilia. |
| first_indexed | 2024-12-10T14:51:31Z |
| format | Article |
| id | doaj.art-9de1d2b5b7e44310a4f476e0089bbc7e |
| institution | Directory Open Access Journal |
| issn | 1738-3536 2005-6184 |
| language | English |
| last_indexed | 2024-12-10T14:51:31Z |
| publishDate | 2018-04-01 |
| publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
| record_format | Article |
| series | Tuberculosis and Respiratory Diseases |
| spelling | doaj.art-9de1d2b5b7e44310a4f476e0089bbc7e2022-12-22T01:44:26ZengThe Korean Academy of Tuberculosis and Respiratory DiseasesTuberculosis and Respiratory Diseases1738-35362005-61842018-04-01812156162Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program RecipientsTae Yun Park, M.D.0Jae-Woo Jung, M.D., Ph.D.1Ju Young Jang, M.D., Ph.D.2Jae Chol Choi, M.D., Ph.D.3 Jong Wook Shin, M.D., Ph.D.,4In Won Park, M.D., Ph.D.5Byoung Whui Choi, M.D., Ph.D. 6Jae Yeol Kim, M.D., Ph.D.7Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.Background Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening program at a tertiary hospital in Korea. Methods Data of private health screening program recipients at the health promotion center of Chung-Ang University Hospital from 2004 to 2013 were collected. Health-related questionnaires and laboratory findings of private health screening program with possible relation with eosinophilia were reviewed. Results of enzyme-linked immunosorbent assay (ELISA) for parasite, chest computed tomography, and pulmonary function test were also reviewed. Results The cumulative prevalence of eosinophilia was 4.0% (1,963 of 48,928). Prevalence of eosinophilia showed a decreased trend from 2004 to 2013. Most cases (96.6%) had mild degree of eosinophilia. Eosinophilic subjects were older and male-predominant. They showed lower levels of forced expiratory volume in 1 second (FEV1%), forced vital capacity (FVC%), and FEV1/FVC than those without eosinophilia. Eosinophilic subjects showed higher positive rate for common parasite in ELISA than those without eosinophilia. On radiologic findings, consolidation and ground glass opacities were positively associated with the degree of eosinophilia. When eosinophil was classified based on severity, statistically significant correlation between the severity of eosinophil and radiologic abnormalities was found. Conclusion Eosinophilia is uncommon in healthy population. It usually occurs at a mild degree. Eosinophilic patients have more radiologic abnormalities compared to those without eosinophilia. Such radiologic abnormalities are associated with the severity of eosinophilia.https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0039&code=0003TRD&vmode=FULLeosinophiliaprevalencetomographyx-ray computed |
| spellingShingle | Tae Yun Park, M.D. Jae-Woo Jung, M.D., Ph.D. Ju Young Jang, M.D., Ph.D. Jae Chol Choi, M.D., Ph.D. Jong Wook Shin, M.D., Ph.D., In Won Park, M.D., Ph.D. Byoung Whui Choi, M.D., Ph.D. Jae Yeol Kim, M.D., Ph.D. Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients Tuberculosis and Respiratory Diseases eosinophilia prevalence tomography x-ray computed |
| title | Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients |
| title_full | Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients |
| title_fullStr | Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients |
| title_full_unstemmed | Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients |
| title_short | Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients |
| title_sort | peripheral eosinophilia and clinico radiological characteristics among health screening program recipients |
| topic | eosinophilia prevalence tomography x-ray computed |
| url | https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0039&code=0003TRD&vmode=FULL |
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