Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses

Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented w...

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Main Authors: Adnan Shaaban MD, Chimaobi Anugwom MBBS, Alma Habib MD, Tetyana Mettler MD, Shahid Jaffer MD, Mary Thomson MD
Format: Article
Language:English
Published: SAGE Publishing 2022-07-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/23247096221111768
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author Adnan Shaaban MD
Chimaobi Anugwom MBBS
Alma Habib MD
Tetyana Mettler MD
Shahid Jaffer MD
Mary Thomson MD
author_facet Adnan Shaaban MD
Chimaobi Anugwom MBBS
Alma Habib MD
Tetyana Mettler MD
Shahid Jaffer MD
Mary Thomson MD
author_sort Adnan Shaaban MD
collection DOAJ
description Primary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.
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spelling doaj.art-9de24de480364b33b26f9999a6097eb82022-12-22T03:42:58ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962022-07-011010.1177/23247096221111768Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver MassesAdnan Shaaban MD0Chimaobi Anugwom MBBS1Alma Habib MD2Tetyana Mettler MD3Shahid Jaffer MD4Mary Thomson MD5University of Minnesota, Minneapolis, USAUniversity of Minnesota, Minneapolis, USAUniversity of Minnesota, Minneapolis, USAUniversity of Minnesota, Minneapolis, USAUniversity of Minnesota, Minneapolis, USAUniversity of Minnesota, Minneapolis, USAPrimary hepatic angiosarcoma (PHA) is a rare and aggressive mesenchymal liver tumor with a poor prognosis and high mortality. Treatment options are limited to palliative chemotherapy with surgical resection reserved for the few cases that present early. We present a case of a patient who presented with jaundice and elevated liver enzymes. Imaging identified a diffusely heterogeneous liver consistent with cirrhosis, findings of portal hypertension, and 2 ill-defined liver lesions. Biopsy results confirmed PHA. Primary hepatic angiosarcoma does not have a typical presentation but should be considered for any patient presenting with an infiltrative liver mass.https://doi.org/10.1177/23247096221111768
spellingShingle Adnan Shaaban MD
Chimaobi Anugwom MBBS
Alma Habib MD
Tetyana Mettler MD
Shahid Jaffer MD
Mary Thomson MD
Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
Journal of Investigative Medicine High Impact Case Reports
title Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
title_full Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
title_fullStr Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
title_full_unstemmed Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
title_short Case of Primary Hepatic Angiosarcoma Presenting With Jaundice and Infiltrative Liver Masses
title_sort case of primary hepatic angiosarcoma presenting with jaundice and infiltrative liver masses
url https://doi.org/10.1177/23247096221111768
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