Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse
The cerebellar cortex comprises a stereotyped array of transverse zones and parasagittal stripes, built around multiple Purkinje cell subtypes, which is highly conserved across birds and mammals. This architecture is revealed in the restricted expression patterns of numerous molecules, in the termin...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-03-01
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| Series: | Frontiers in Systems Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00041/full |
| _version_ | 1819013994527064064 |
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| author | Richard eHawkes |
| author_facet | Richard eHawkes |
| author_sort | Richard eHawkes |
| collection | DOAJ |
| description | The cerebellar cortex comprises a stereotyped array of transverse zones and parasagittal stripes, built around multiple Purkinje cell subtypes, which is highly conserved across birds and mammals. This architecture is revealed in the restricted expression patterns of numerous molecules, in the terminal fields of the afferent projections, in the distribution of interneurons, and in the functional organization. This review provides an overview of cerebellar architecture with an emphasis on recent attempts to relate molecular architecture to function – in particular, the expression of long-term depression at the parallel fiber-Purkinje cell synapse. |
| first_indexed | 2024-12-21T02:08:47Z |
| format | Article |
| id | doaj.art-9de3114b68ea453d990b5fe3791855fb |
| institution | Directory Open Access Journal |
| issn | 1662-5137 |
| language | English |
| last_indexed | 2024-12-21T02:08:47Z |
| publishDate | 2014-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Systems Neuroscience |
| spelling | doaj.art-9de3114b68ea453d990b5fe3791855fb2022-12-21T19:19:26ZengFrontiers Media S.A.Frontiers in Systems Neuroscience1662-51372014-03-01810.3389/fnsys.2014.0004178665Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell SynapseRichard eHawkes0University of CalgaryThe cerebellar cortex comprises a stereotyped array of transverse zones and parasagittal stripes, built around multiple Purkinje cell subtypes, which is highly conserved across birds and mammals. This architecture is revealed in the restricted expression patterns of numerous molecules, in the terminal fields of the afferent projections, in the distribution of interneurons, and in the functional organization. This review provides an overview of cerebellar architecture with an emphasis on recent attempts to relate molecular architecture to function – in particular, the expression of long-term depression at the parallel fiber-Purkinje cell synapse.http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00041/fullPurkinje cellLong-term depressionzebrin IIstripesphospholipase Cß4 |
| spellingShingle | Richard eHawkes Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse Frontiers in Systems Neuroscience Purkinje cell Long-term depression zebrin II stripes phospholipase Cß4 |
| title | Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse |
| title_full | Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse |
| title_fullStr | Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse |
| title_full_unstemmed | Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse |
| title_short | Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse |
| title_sort | purkinje cell stripes and long term depression at the parallel fiber purkinje cell synapse |
| topic | Purkinje cell Long-term depression zebrin II stripes phospholipase Cß4 |
| url | http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00041/full |
| work_keys_str_mv | AT richardehawkes purkinjecellstripesandlongtermdepressionattheparallelfiberpurkinjecellsynapse |