Safety of intracoronary infusion of 20 million C-kit positive human cardiac stem cells in pigs.

Safety of intracoronary infusion of 20 million C-kit positive human cardiac stem cells in pigs.

There is mounting interest in using c-kit positive human cardiac stem cells (c-kit(pos) hCSCs) to repair infarcted myocardium in patients with ischemic cardiomyopathy. A recent phase I clinical trial (SCIPIO) has shown that intracoronary infusion of 1 million hCSCs is safe. Higher doses of CSCs may...

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Bibliographic Details
Main Authors: Matthew C L Keith, Xian-Liang Tang, Yukichi Tokita, Qian-Hong Li, Shahab Ghafghazi, Joseph Moore Iv, Kyung U Hong, Brandon Elmore, Alok Amraotkar, Brian L Ganzel, Kendra J Grubb, Michael P Flaherty, Gregory Hunt, Bathri Vajravelu, Marcin Wysoczynski, Roberto Bolli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4408046?pdf=render

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