ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT
Mantle cell lymphoma (MCL) is a subtype of non-Hodgkin lymphoma that presents in a disseminated state at diagnosis. Multiple extranodal site involvement is frequent, however genitourinary system is rarely affected, being kidneys the most common location. Besides lymphoid cell infiltrations of kidney...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1827 |
| _version_ | 1826911407942139904 |
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| author | Maria Julia Montoro Elias Alejandro Jatem Pau Abrisqueta Nerea Castillo Maria Teresa Salcedo Josepa Vila |
| author_facet | Maria Julia Montoro Elias Alejandro Jatem Pau Abrisqueta Nerea Castillo Maria Teresa Salcedo Josepa Vila |
| author_sort | Maria Julia Montoro |
| collection | DOAJ |
| description | Mantle cell lymphoma (MCL) is a subtype of non-Hodgkin lymphoma that presents in a disseminated state at diagnosis. Multiple extranodal site involvement is frequent, however genitourinary system is rarely affected, being kidneys the most common location. Besides lymphoid cell infiltrations of kidneys, glomerulonephritides are a known disorder associated with non-Hodgkin lymphomas (LNH). Membranoproliferative glomerulonephritis is the most common cause of nephrotic syndrome in these cases. Herein we report a patient who presented acute renal failure, haematuria and subnephrotic range proteinuria due to mebranoproliferative glomerulonephritis and tumoral cell infiltration demonstrated by renal biopsy, in association MCL. Patient´s renal function improved, hematuria and proteinuria resolved after specific lymphoma treatment.
Although membranoproliferative glomerulonephritis has been reported to occur in association with non-Hodking´s lymphoma, information concerning the correct treatment of the glomerular disease is limited. Specific lymphoma treatment, unlike the primary forms, constitutes the cornerstone in the management of this glomerular disease, with remission and recurrence that usually runs parallel to the course of the lymphoid malignancy. |
| first_indexed | 2024-12-24T00:41:43Z |
| format | Article |
| id | doaj.art-9de8c2c640ce439ebe77bb4c2df6d738 |
| institution | Directory Open Access Journal |
| issn | 2035-3006 |
| language | English |
| last_indexed | 2025-02-17T10:14:12Z |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj.art-9de8c2c640ce439ebe77bb4c2df6d7382025-01-02T00:30:12ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORTMaria Julia Montoro0Elias Alejandro Jatem1Pau Abrisqueta2Nerea Castillo3Maria Teresa Salcedo4Josepa Vila5Hospital Universitari Vall d´Hebron. Servicio de HematologíaHospital Universitari Vall d´Hebron. Servicio de NefrologíaHospital Universitari Vall d´Hebron. Servicio de HematologíaHospital Universitari Vall d´Hebron. Servicio de HematologíaHospital Universitari Vall d´Hebron. Servicio de PatologíaHospital Universitari Vall d´Hebron. Servicio de NefrologíaMantle cell lymphoma (MCL) is a subtype of non-Hodgkin lymphoma that presents in a disseminated state at diagnosis. Multiple extranodal site involvement is frequent, however genitourinary system is rarely affected, being kidneys the most common location. Besides lymphoid cell infiltrations of kidneys, glomerulonephritides are a known disorder associated with non-Hodgkin lymphomas (LNH). Membranoproliferative glomerulonephritis is the most common cause of nephrotic syndrome in these cases. Herein we report a patient who presented acute renal failure, haematuria and subnephrotic range proteinuria due to mebranoproliferative glomerulonephritis and tumoral cell infiltration demonstrated by renal biopsy, in association MCL. Patient´s renal function improved, hematuria and proteinuria resolved after specific lymphoma treatment. Although membranoproliferative glomerulonephritis has been reported to occur in association with non-Hodking´s lymphoma, information concerning the correct treatment of the glomerular disease is limited. Specific lymphoma treatment, unlike the primary forms, constitutes the cornerstone in the management of this glomerular disease, with remission and recurrence that usually runs parallel to the course of the lymphoid malignancy.https://mjhid.org/index.php/mjhid/article/view/1827Non-Hodgkin lymphomaMantle cell lymphomaProteinuriaMembranoproliferative glomerulonephritis. |
| spellingShingle | Maria Julia Montoro Elias Alejandro Jatem Pau Abrisqueta Nerea Castillo Maria Teresa Salcedo Josepa Vila ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT Mediterranean Journal of Hematology and Infectious Diseases Non-Hodgkin lymphoma Mantle cell lymphoma Proteinuria Membranoproliferative glomerulonephritis. |
| title | ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT |
| title_full | ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT |
| title_fullStr | ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT |
| title_full_unstemmed | ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT |
| title_short | ACUTE RENAL FAILURE DUE TO MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AND TUMORAL CELL INFILTRATION IN A PATIENT WITH MANTLE CELL LYMPHOMA: A CASE REPORT |
| title_sort | acute renal failure due to membranoproliferative glomerulonephritis and tumoral cell infiltration in a patient with mantle cell lymphoma a case report |
| topic | Non-Hodgkin lymphoma Mantle cell lymphoma Proteinuria Membranoproliferative glomerulonephritis. |
| url | https://mjhid.org/index.php/mjhid/article/view/1827 |
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