Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report

Renal cell cancer (RCC) in renal allograft is a rare entity. We report a case of RCC successfully diagnosed in a 42-year-old renal allograft recipient which developed 13 years after engraftment. The patient was initially evaluated using ultrasound for two episodes of hematuria followed by contrast-e...

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Main Authors: Shashank Agrawal, Aditya Parikh, Ravindra B Sabnis, Mahesh R Desai
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Journal of Transplantation
Subjects:
Online Access:http://www.ijtonline.in/article.asp?issn=2212-0017;year=2022;volume=16;issue=4;spage=438;epage=440;aulast=Agrawal
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author Shashank Agrawal
Aditya Parikh
Ravindra B Sabnis
Mahesh R Desai
author_facet Shashank Agrawal
Aditya Parikh
Ravindra B Sabnis
Mahesh R Desai
author_sort Shashank Agrawal
collection DOAJ
description Renal cell cancer (RCC) in renal allograft is a rare entity. We report a case of RCC successfully diagnosed in a 42-year-old renal allograft recipient which developed 13 years after engraftment. The patient was initially evaluated using ultrasound for two episodes of hematuria followed by contrast-enhanced CT scan revealing 9.7 cm × 8.6 cm × 6.5 cm heterogeneously enhancing mass at mid-pole with involvement of renal sinus. Allograft nephrectomy was performed. A genetic study with DNA microsatellite analysis showed de novo RCC from donor origin. Seven months after surgery, the patient is alive with no evidence of tumor recurrence and is now planned for a second renal transplant. To the best of our knowledge, this is the largest allograft RCC reported in the Indian scenario.
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spelling doaj.art-9ded671fd77740c78cda7a31415846ad2023-01-12T12:11:20ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252022-01-0116443844010.4103/ijot.ijot_37_21Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case reportShashank AgrawalAditya ParikhRavindra B SabnisMahesh R DesaiRenal cell cancer (RCC) in renal allograft is a rare entity. We report a case of RCC successfully diagnosed in a 42-year-old renal allograft recipient which developed 13 years after engraftment. The patient was initially evaluated using ultrasound for two episodes of hematuria followed by contrast-enhanced CT scan revealing 9.7 cm × 8.6 cm × 6.5 cm heterogeneously enhancing mass at mid-pole with involvement of renal sinus. Allograft nephrectomy was performed. A genetic study with DNA microsatellite analysis showed de novo RCC from donor origin. Seven months after surgery, the patient is alive with no evidence of tumor recurrence and is now planned for a second renal transplant. To the best of our knowledge, this is the largest allograft RCC reported in the Indian scenario.http://www.ijtonline.in/article.asp?issn=2212-0017;year=2022;volume=16;issue=4;spage=438;epage=440;aulast=Agrawalallograftde novoposttransplantrenal cell carcinoma
spellingShingle Shashank Agrawal
Aditya Parikh
Ravindra B Sabnis
Mahesh R Desai
Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
Indian Journal of Transplantation
allograft
de novo
posttransplant
renal cell carcinoma
title Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
title_full Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
title_fullStr Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
title_full_unstemmed Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
title_short Large de novo renal cell cancer in renal allograft: Rare case report and review of literature - A case report
title_sort large de novo renal cell cancer in renal allograft rare case report and review of literature a case report
topic allograft
de novo
posttransplant
renal cell carcinoma
url http://www.ijtonline.in/article.asp?issn=2212-0017;year=2022;volume=16;issue=4;spage=438;epage=440;aulast=Agrawal
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AT ravindrabsabnis largedenovorenalcellcancerinrenalallograftrarecasereportandreviewofliteratureacasereport
AT maheshrdesai largedenovorenalcellcancerinrenalallograftrarecasereportandreviewofliteratureacasereport