Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon
The aim of review. To generalize literature data on endoscopic and morphological diagnostics of serrated adenomas of the colon. Key points. In 2010 a new variant of histological classification of colonic tumors have been accepted by WHO, according to which serrated neoplasms were defined as separate...
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Language: | Russian |
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Gastro LLC
2016-08-01
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Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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Online Access: | https://www.gastro-j.ru/jour/article/view/27 |
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author | A. M. Nechipay M. V. Zobnina L. M. Cherkasova I. B. Perfilyev V. A. Krivopuskov |
author_facet | A. M. Nechipay M. V. Zobnina L. M. Cherkasova I. B. Perfilyev V. A. Krivopuskov |
author_sort | A. M. Nechipay |
collection | DOAJ |
description | The aim of review. To generalize literature data on endoscopic and morphological diagnostics of serrated adenomas of the colon. Key points. In 2010 a new variant of histological classification of colonic tumors have been accepted by WHO, according to which serrated neoplasms were defined as separate group of preneoplastic changes, along with colonic adenomas. At the present time hyperplastic polyps and other serrated neoplasms are considered to be precursor lesions for 15 to 20% of sporadic or asymptomatic colorectal cancers located mainly in proximal colon, that progress by specific serrated adenoma-related pathway. Diagnostics of such lesions both on microscopic and macroscopical levels is associated with significant difficulties due to absence of the uniform nomenclature, definite morphological features and endoscopic semiotics. Conclusion. Definition of main morphological and endoscopic diagnostic criteria of all types of serrated adenomas will provide successful diagnostics along with differentiation with other epithelial colonic lesions that is required for proper choice of management approach. |
first_indexed | 2024-03-08T09:22:16Z |
format | Article |
id | doaj.art-9dedd13ac1554f02b3550162aabcb7fb |
institution | Directory Open Access Journal |
issn | 1382-4376 2658-6673 |
language | Russian |
last_indexed | 2024-04-24T19:23:15Z |
publishDate | 2016-08-01 |
publisher | Gastro LLC |
record_format | Article |
series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
spelling | doaj.art-9dedd13ac1554f02b3550162aabcb7fb2024-03-25T16:53:07ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732016-08-0126110711510.22416/1382-4376-2016-26-1-107-11527Morphological and endoscopic diagnostic criteria of serrated adenomas of the colonA. M. Nechipay0M. V. Zobnina1L. M. Cherkasova2I. B. Perfilyev3V. A. Krivopuskov4Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57Federal government-financed institution «Polyclinic # 1», General affairs departments of the President of the Russian Federation, Moscow, the Russian Federation State educational state-funded institution «Russian medical academy of postgraduate education», Ministry of healthcare of the Russian Federation, Moscow, the Russian Federation; Federal government-financed healthcare institution «City clinical hospital #57», Moscow, the Russian Federation Municipal Hospital № 57The aim of review. To generalize literature data on endoscopic and morphological diagnostics of serrated adenomas of the colon. Key points. In 2010 a new variant of histological classification of colonic tumors have been accepted by WHO, according to which serrated neoplasms were defined as separate group of preneoplastic changes, along with colonic adenomas. At the present time hyperplastic polyps and other serrated neoplasms are considered to be precursor lesions for 15 to 20% of sporadic or asymptomatic colorectal cancers located mainly in proximal colon, that progress by specific serrated adenoma-related pathway. Diagnostics of such lesions both on microscopic and macroscopical levels is associated with significant difficulties due to absence of the uniform nomenclature, definite morphological features and endoscopic semiotics. Conclusion. Definition of main morphological and endoscopic diagnostic criteria of all types of serrated adenomas will provide successful diagnostics along with differentiation with other epithelial colonic lesions that is required for proper choice of management approach.https://www.gastro-j.ru/jour/article/view/27колоректальный ракзубчатые аденомыэндоскопическая диагностика |
spellingShingle | A. M. Nechipay M. V. Zobnina L. M. Cherkasova I. B. Perfilyev V. A. Krivopuskov Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon Российский журнал гастроэнтерологии, гепатологии, колопроктологии колоректальный рак зубчатые аденомы эндоскопическая диагностика |
title | Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
title_full | Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
title_fullStr | Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
title_full_unstemmed | Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
title_short | Morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
title_sort | morphological and endoscopic diagnostic criteria of serrated adenomas of the colon |
topic | колоректальный рак зубчатые аденомы эндоскопическая диагностика |
url | https://www.gastro-j.ru/jour/article/view/27 |
work_keys_str_mv | AT amnechipay morphologicalandendoscopicdiagnosticcriteriaofserratedadenomasofthecolon AT mvzobnina morphologicalandendoscopicdiagnosticcriteriaofserratedadenomasofthecolon AT lmcherkasova morphologicalandendoscopicdiagnosticcriteriaofserratedadenomasofthecolon AT ibperfilyev morphologicalandendoscopicdiagnosticcriteriaofserratedadenomasofthecolon AT vakrivopuskov morphologicalandendoscopicdiagnosticcriteriaofserratedadenomasofthecolon |