Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents

A novel series of carbamothioylamino-benzene-sulfonamide-thiophene-carboxylates 4a-c and thieno[3,2-d]pyrimidin-2-yl-amino-benzene-sulfonamides 5a-c were synthesized in a series of synthetic steps and were used as key intermediates for the synthesis of thienotriazolopyrimidine-benzene-sulfonamide de...

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Bibliographic Details
Main Authors: Hafez Hend N., Alsalamah Sulaiman A., El-Gazzar Abdel-Rhman B. A.
Format: Article
Language:English
Published: Sciendo 2017-09-01
Series:Acta Pharmaceutica
Subjects:
thieno[3,2-d]pyrimidines
thieno[3,2-d][1,2,4]triazolo[1,5-a]pyrimidines
anticancer
antibacterial
Online Access:https://doi.org/10.1515/acph-2017-0028

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