Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs

Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs

Infection of pigs with the African swine fever virus (ASFV) leads to a devastating hemorrhagic disease with a high mortality of up to 100%. In this study, a CD2v gene deletion was introduced to a genotype IX virus from East Africa, ASFV-Kenya-IX-1033 (ASFV-Kenya-IX-1033-∆CD2v), to investigate whethe...

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Bibliographic Details
Main Authors: Johanneke D. Hemmink, Emmanuel M. Khazalwa, Hussein M. Abkallo, Bernard Oduor, Jeremiah Khayumbi, Nicholas Svitek, Sonal P. Henson, Sandra Blome, Günther Keil, Richard P. Bishop, Lucilla Steinaa
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
African swine fever
CD2v
vaccine
gene deletion
Online Access:https://www.mdpi.com/1999-4915/14/9/1917

Internet

https://www.mdpi.com/1999-4915/14/9/1917

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