Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor
Abstract We report a case of ultrasound-guided ex vivo oocyte retrieval for fertility preservation in a woman with bilateral borderline ovarian tumor, for whom conventional transvaginal oocyte retrieval was deemed unsafe because of the increased risk of malignant cell spillage. Ovarian stimulation w...
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| Format: | Article |
| Language: | English |
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Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
2021-05-01
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| Series: | Revista Brasileira de Ginecologia e Obstetrícia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000300225&tlng=en |
| _version_ | 1818988317050404864 |
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| author | Bruno Ramalho de Carvalho Geórgia Fontes Cintra Taise Moura Franceschi Íris de Oliveira Cabral Leandro Santos de Araújo Resende Brenda Pires Gumz Thiago David Alves Pinto |
| author_facet | Bruno Ramalho de Carvalho Geórgia Fontes Cintra Taise Moura Franceschi Íris de Oliveira Cabral Leandro Santos de Araújo Resende Brenda Pires Gumz Thiago David Alves Pinto |
| author_sort | Bruno Ramalho de Carvalho |
| collection | DOAJ |
| description | Abstract We report a case of ultrasound-guided ex vivo oocyte retrieval for fertility preservation in a woman with bilateral borderline ovarian tumor, for whom conventional transvaginal oocyte retrieval was deemed unsafe because of the increased risk of malignant cell spillage. Ovarian stimulation with gonadotropins was performed. Surgery was scheduled according to the ovarian response to exogenous gonadotropic stimulation; oophorectomized specimens were obtained by laparoscopy, and oocyte retrieval was performed ~ 37 hours after the ovulatory trigger. The sum of 20 ovarian follicles were aspirated, and 16 oocytes were obtained.We performed vitrification of 12 metaphase II oocytes and 3 oocytes matured in vitro. Our result emphasizes the viability of ex vivo mature oocyte retrieval after controlled ovarian stimulation for those with high risk of malignant dissemination by conventional approach. |
| first_indexed | 2024-12-20T19:20:39Z |
| format | Article |
| id | doaj.art-9def99d8889244e6b22e2f4b66e156f2 |
| institution | Directory Open Access Journal |
| issn | 0100-7203 |
| language | English |
| last_indexed | 2024-12-20T19:20:39Z |
| publishDate | 2021-05-01 |
| publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
| record_format | Article |
| series | Revista Brasileira de Ginecologia e Obstetrícia |
| spelling | doaj.art-9def99d8889244e6b22e2f4b66e156f22022-12-21T19:29:00ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032021-05-0143322523110.1055/s-0040-1718436Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian TumorBruno Ramalho de Carvalhohttps://orcid.org/0000-0002-1554-9499Geórgia Fontes Cintrahttps://orcid.org/0000-0002-6463-7268Taise Moura Franceschihttps://orcid.org/0000-0003-4499-6965Íris de Oliveira Cabralhttps://orcid.org/0000-0001-8166-5095Leandro Santos de Araújo Resendehttps://orcid.org/0000-0001-8186-4051Brenda Pires Gumzhttps://orcid.org/0000-0001-7796-1780Thiago David Alves Pintohttps://orcid.org/0000-0001-6347-0980Abstract We report a case of ultrasound-guided ex vivo oocyte retrieval for fertility preservation in a woman with bilateral borderline ovarian tumor, for whom conventional transvaginal oocyte retrieval was deemed unsafe because of the increased risk of malignant cell spillage. Ovarian stimulation with gonadotropins was performed. Surgery was scheduled according to the ovarian response to exogenous gonadotropic stimulation; oophorectomized specimens were obtained by laparoscopy, and oocyte retrieval was performed ~ 37 hours after the ovulatory trigger. The sum of 20 ovarian follicles were aspirated, and 16 oocytes were obtained.We performed vitrification of 12 metaphase II oocytes and 3 oocytes matured in vitro. Our result emphasizes the viability of ex vivo mature oocyte retrieval after controlled ovarian stimulation for those with high risk of malignant dissemination by conventional approach.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000300225&tlng=encryopreservationex vivo oocyte retrievalfertility preservationovarian cancerborderline ovarian tumorvitrification |
| spellingShingle | Bruno Ramalho de Carvalho Geórgia Fontes Cintra Taise Moura Franceschi Íris de Oliveira Cabral Leandro Santos de Araújo Resende Brenda Pires Gumz Thiago David Alves Pinto Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor Revista Brasileira de Ginecologia e Obstetrícia cryopreservation ex vivo oocyte retrieval fertility preservation ovarian cancer borderline ovarian tumor vitrification |
| title | Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor |
| title_full | Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor |
| title_fullStr | Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor |
| title_full_unstemmed | Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor |
| title_short | Ex vivo Retrieval of Mature Oocytes for Fertility Preservation in a Patient with Bilateral Borderline Ovarian Tumor |
| title_sort | ex vivo retrieval of mature oocytes for fertility preservation in a patient with bilateral borderline ovarian tumor |
| topic | cryopreservation ex vivo oocyte retrieval fertility preservation ovarian cancer borderline ovarian tumor vitrification |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000300225&tlng=en |
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