Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas
<p>Abstract</p> <p>Background</p> <p>DNA repair genes critically regulate the cellular response to chemotherapy and epigenetic regulation of these genes may be influenced by chemotherapy exposure. Restoration of BRCA1 and BRCA2 mediates resistance to platinum chemothera...
Main Authors: | Walsh Tom, Garcia Rochelle L, Taniguchi Toshiyasu, Gonzalez Rachel M, Swisher Elizabeth M, Goff Barbara A, Welcsh Piri |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-07-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/8/1/48 |
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