Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review
Abstract Background The present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) of several frequent and established PROMs used to assess patients who have undergone TKA. This study was...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Knee Surgery & Related Research |
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| Online Access: | https://doi.org/10.1186/s43019-024-00210-z |
| _version_ | 1797355663680077824 |
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| author | Filippo Migliorini Nicola Maffulli Luise Schäfer Francesco Simeone Andreas Bell Ulf Krister Hofmann |
| author_facet | Filippo Migliorini Nicola Maffulli Luise Schäfer Francesco Simeone Andreas Bell Ulf Krister Hofmann |
| author_sort | Filippo Migliorini |
| collection | DOAJ |
| description | Abstract Background The present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) of several frequent and established PROMs used to assess patients who have undergone TKA. This study was conducted according to the 2020 PRISMA statement. Methods In September 2023, PubMed, Web of Science, and Embase were accessed with no time constraint All clinical studies investigating tools to assess the clinical relevance of PROMs used to evaluate patients having received TKA were accessed. Only studies which evaluated the MCID, PASS, or SCB were eligible. The PROMs of interest were the Forgotten Joint Score-12 (FJS-12), the Oxford Knee Score (OKS), the Knee Injury and Osteoarthritis Outcome Score (KOOS) and its related subscales activity of daily living (ADL), pain, quality of life (QoL), sports and recreational activities, and symptoms, the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) score, the Knee Society Score (KSS) and related function score, and the Short Form-12 (SF-12) and Short Form-36 (SF-36). Results Data from 29,737 patients were collected. The overall risk of bias was low to moderate. The great variability of thresholds for MCID, SCB and PASS between questionnaires but also between investigated aspects was noted, whereby MCIDs for the SF-36 appear lower than for knee-specific questionnaires. Conclusion Despite its critical role from a patient’s perspective, the dimension of SCB is still neglected in the literature. Moreover, thresholds for the different concepts need to be condition-specific. We encourage authors to specifically report such data in future studies and to adhere to previously reported definitions to allow future comparison. Level of evidence Level IV, systematic review and meta-analysis |
| first_indexed | 2024-03-08T14:15:21Z |
| format | Article |
| id | doaj.art-9dffcf9d61b9447e83e04c9d14450338 |
| institution | Directory Open Access Journal |
| issn | 2234-2451 |
| language | English |
| last_indexed | 2024-03-08T14:15:21Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Knee Surgery & Related Research |
| spelling | doaj.art-9dffcf9d61b9447e83e04c9d144503382024-01-14T12:27:34ZengBMCKnee Surgery & Related Research2234-24512024-01-013611910.1186/s43019-024-00210-zMinimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic reviewFilippo Migliorini0Nicola Maffulli1Luise Schäfer2Francesco Simeone3Andreas Bell4Ulf Krister Hofmann5Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Medical CentreDepartment of Trauma and Orthopaedic Surgery, Faculty of Medicine and Psychology, University la SapienzaDepartment of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Medical CentreDepartment of Orthopedics and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical UniversityDepartment of Orthopaedic and Trauma Surgery, Eifelklinik St.BrigidaDepartment of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Medical CentreAbstract Background The present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) of several frequent and established PROMs used to assess patients who have undergone TKA. This study was conducted according to the 2020 PRISMA statement. Methods In September 2023, PubMed, Web of Science, and Embase were accessed with no time constraint All clinical studies investigating tools to assess the clinical relevance of PROMs used to evaluate patients having received TKA were accessed. Only studies which evaluated the MCID, PASS, or SCB were eligible. The PROMs of interest were the Forgotten Joint Score-12 (FJS-12), the Oxford Knee Score (OKS), the Knee Injury and Osteoarthritis Outcome Score (KOOS) and its related subscales activity of daily living (ADL), pain, quality of life (QoL), sports and recreational activities, and symptoms, the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) score, the Knee Society Score (KSS) and related function score, and the Short Form-12 (SF-12) and Short Form-36 (SF-36). Results Data from 29,737 patients were collected. The overall risk of bias was low to moderate. The great variability of thresholds for MCID, SCB and PASS between questionnaires but also between investigated aspects was noted, whereby MCIDs for the SF-36 appear lower than for knee-specific questionnaires. Conclusion Despite its critical role from a patient’s perspective, the dimension of SCB is still neglected in the literature. Moreover, thresholds for the different concepts need to be condition-specific. We encourage authors to specifically report such data in future studies and to adhere to previously reported definitions to allow future comparison. Level of evidence Level IV, systematic review and meta-analysishttps://doi.org/10.1186/s43019-024-00210-zKneeArthroplastyPatient-reported outcome measuresPROMsMCIDSCB |
| spellingShingle | Filippo Migliorini Nicola Maffulli Luise Schäfer Francesco Simeone Andreas Bell Ulf Krister Hofmann Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review Knee Surgery & Related Research Knee Arthroplasty Patient-reported outcome measures PROMs MCID SCB |
| title | Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review |
| title_full | Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review |
| title_fullStr | Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review |
| title_full_unstemmed | Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review |
| title_short | Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review |
| title_sort | minimal clinically important difference mcid substantial clinical benefit scb and patient acceptable symptom state pass in patients who have undergone total knee arthroplasty a systematic review |
| topic | Knee Arthroplasty Patient-reported outcome measures PROMs MCID SCB |
| url | https://doi.org/10.1186/s43019-024-00210-z |
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