Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease
Studies of metabolites in neurodegeneration have not yet used sebum as a source fluid. Here the authors demonstrate the potential of metabolomics of sebum samples from individuals with Parkinson’s disease and controls.
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21669-4 |
| _version_ | 1818998190426292224 |
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| author | Eleanor Sinclair Drupad K. Trivedi Depanjan Sarkar Caitlin Walton-Doyle Joy Milne Tilo Kunath Anouk M. Rijs Rob M. A. de Bie Royston Goodacre Monty Silverdale Perdita Barran |
| author_facet | Eleanor Sinclair Drupad K. Trivedi Depanjan Sarkar Caitlin Walton-Doyle Joy Milne Tilo Kunath Anouk M. Rijs Rob M. A. de Bie Royston Goodacre Monty Silverdale Perdita Barran |
| author_sort | Eleanor Sinclair |
| collection | DOAJ |
| description | Studies of metabolites in neurodegeneration have not yet used sebum as a source fluid. Here the authors demonstrate the potential of metabolomics of sebum samples from individuals with Parkinson’s disease and controls. |
| first_indexed | 2024-12-20T21:57:35Z |
| format | Article |
| id | doaj.art-9e01bc89a95e413fbdff0e9ee7e5a51b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T21:57:35Z |
| publishDate | 2021-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9e01bc89a95e413fbdff0e9ee7e5a51b2022-12-21T19:25:25ZengNature PortfolioNature Communications2041-17232021-03-011211910.1038/s41467-021-21669-4Metabolomics of sebum reveals lipid dysregulation in Parkinson’s diseaseEleanor Sinclair0Drupad K. Trivedi1Depanjan Sarkar2Caitlin Walton-Doyle3Joy Milne4Tilo Kunath5Anouk M. Rijs6Rob M. A. de Bie7Royston Goodacre8Monty Silverdale9Perdita Barran10Manchester Institute of Biotechnology, School of Chemistry, The University of ManchesterManchester Institute of Biotechnology, School of Chemistry, The University of ManchesterManchester Institute of Biotechnology, School of Chemistry, The University of ManchesterManchester Institute of Biotechnology, School of Chemistry, The University of ManchesterManchester Institute of Biotechnology, School of Chemistry, The University of ManchesterInstitute for Stem Cell Research, School of Biological Sciences, The University of EdinburghDivision of BioAnalytical Chemistry, AIMMS Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit AmsterdamDepartment of Neurology, Amsterdam Neuroscience, Amsterdam University Medical Centers, University of AmsterdamInstitute of Systems, Molecular and Integrative Biology, Department of Biochemistry and Systems Biology, University of LiverpoolDepartment of Neurology, Salford Royal Foundation Trust, Manchester Academic Health Science Centre, University of ManchesterManchester Institute of Biotechnology, School of Chemistry, The University of ManchesterStudies of metabolites in neurodegeneration have not yet used sebum as a source fluid. Here the authors demonstrate the potential of metabolomics of sebum samples from individuals with Parkinson’s disease and controls.https://doi.org/10.1038/s41467-021-21669-4 |
| spellingShingle | Eleanor Sinclair Drupad K. Trivedi Depanjan Sarkar Caitlin Walton-Doyle Joy Milne Tilo Kunath Anouk M. Rijs Rob M. A. de Bie Royston Goodacre Monty Silverdale Perdita Barran Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease Nature Communications |
| title | Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease |
| title_full | Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease |
| title_fullStr | Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease |
| title_full_unstemmed | Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease |
| title_short | Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease |
| title_sort | metabolomics of sebum reveals lipid dysregulation in parkinson s disease |
| url | https://doi.org/10.1038/s41467-021-21669-4 |
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