Two circPPFIA1s negatively regulate liver metastasis of colon cancer via miR-155-5p/CDX1 and HuR/RAB36

Two circPPFIA1s negatively regulate liver metastasis of colon cancer via miR-155-5p/CDX1 and HuR/RAB36

Abstract Background Circular RNAs (circRNAs) play a critical role in colorectal cancer (CRC) progression, including metastasis. However, the detailed molecular mechanism is not fully understood. Methods Differentially expressed circRNAs between primary KM12C and liver metastatic KM12L4 colon cancer...

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Bibliographic Details
Main Authors: Haein Ji, Tae Won Kim, Woo Joo Lee, Seong Dong Jeong, Yong Beom Cho, Hyeon Ho Kim
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
Liver metastasis
circPPFIA1
miR-155-5p
CDX1
HuR
Online Access:https://doi.org/10.1186/s12943-022-01667-w

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