Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
The genotoxic potential of glucocorticoid receptor (GR)-targeted liposomal formulations of the anticancer drug molecule ESC8 was studied in vivo. A methodical literature review discovered no previous studies on the genotoxicity of ESC8. Genotoxicity was assessed in both male and female mice by vario...
Main Authors: | Ajaz Ahmad, Basit Latief Jan, Mohammad Raish, Hari Krishna Reddy Rachamalla, Rajkumar Banerjee, Debabrata Mukhopadhyay, Khalid M. Alkharfy |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Saudi Pharmaceutical Journal |
Online Access: | http://www.sciencedirect.com/science/article/pii/S131901641930043X |
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