Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases
Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-sp...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/12/10/931 |
| _version_ | 1797552231612940288 |
|---|---|
| author | N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park |
| author_facet | N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park |
| author_sort | N.Vijayakameswara Rao |
| collection | DOAJ |
| description | Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases. |
| first_indexed | 2024-03-10T15:57:01Z |
| format | Article |
| id | doaj.art-9e03fc19f78941fa8242985ca8e80e0d |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T15:57:01Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-9e03fc19f78941fa8242985ca8e80e0d2023-11-20T15:33:59ZengMDPI AGPharmaceutics1999-49232020-09-01121093110.3390/pharmaceutics12100931Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory DiseasesN.Vijayakameswara Rao0Jun Gi Rho1Wooram Um2Pramod Kumar EK3Van Quy Nguyen4Byeong Hoon Oh5Wook Kim6Jae Hyung Park7School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaDepartment of Molecular Science & Technology, Ajou University, Suwon 16499, KoreaSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, KoreaOwing to their unique biological functions, hyaluronic acid (HA) and its derivatives have been explored extensively for biomedical applications such as tissue engineering, drug delivery, and molecular imaging. In particular, self-assembled HA nanoparticles (HA-NPs) have been used widely as target-specific and long-acting nanocarriers for the delivery of a wide range of therapeutic or diagnostic agents. Recently, it has been demonstrated that empty HA-NPs without bearing any therapeutic agent can be used therapeutically for the treatment of inflammatory diseases via modulating inflammatory responses. In this review, we aim to provide an overview of the significant achievements in this field and highlight the potential of HA-NPs for the treatment of inflammatory diseases.https://www.mdpi.com/1999-4923/12/10/931hyaluronic aciddrug conjugatespolymeric nanoparticlestumor-targetingtargeted-therapyinflammatory diseases |
| spellingShingle | N.Vijayakameswara Rao Jun Gi Rho Wooram Um Pramod Kumar EK Van Quy Nguyen Byeong Hoon Oh Wook Kim Jae Hyung Park Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases Pharmaceutics hyaluronic acid drug conjugates polymeric nanoparticles tumor-targeting targeted-therapy inflammatory diseases |
| title | Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases |
| title_full | Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases |
| title_fullStr | Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases |
| title_full_unstemmed | Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases |
| title_short | Hyaluronic Acid Nanoparticles as Nanomedicine for Treatment of Inflammatory Diseases |
| title_sort | hyaluronic acid nanoparticles as nanomedicine for treatment of inflammatory diseases |
| topic | hyaluronic acid drug conjugates polymeric nanoparticles tumor-targeting targeted-therapy inflammatory diseases |
| url | https://www.mdpi.com/1999-4923/12/10/931 |
| work_keys_str_mv | AT nvijayakameswararao hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT jungirho hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT wooramum hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT pramodkumarek hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT vanquynguyen hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT byeonghoonoh hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT wookkim hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases AT jaehyungpark hyaluronicacidnanoparticlesasnanomedicinefortreatmentofinflammatorydiseases |