Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic
Microorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high requirement and demand for the development of safety products finished with antimicrobial properties. The study involves the antimicrobial activity of...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-11-01
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| Series: | Journal of Materials Research and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785421010012 |
| _version_ | 1819099392877002752 |
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| author | K.M. Archana Revathy Rajagopal Veena Gayathri Krishnaswamy S. Aishwarya |
| author_facet | K.M. Archana Revathy Rajagopal Veena Gayathri Krishnaswamy S. Aishwarya |
| author_sort | K.M. Archana |
| collection | DOAJ |
| description | Microorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high requirement and demand for the development of safety products finished with antimicrobial properties. The study involves the antimicrobial activity of natural cotton coated with copper iodide capped with Hibiscus rosa-sinensis L. flower extract (CuI-FE) which is rich in anthocyanin, cyanidin-3-sophoroside by ultrasonication method. The coated and uncoated cotton fabric was characterised through XRD, SEM, AFM, tensile strength and UV–Visible spectroscopic techniques. XRD confirmed the formation of CuI particles, SEM showed that CuI-FE was prismatic in shape. The average size of CuI-FE particles was found to be 552.45 nm. Anti-bacterial studies showed copper iodide particles to be a potent antimicrobial agent. AFM images confirmed the rupture of bacterial cell walls in the presence of prismatic CuI-FE. In-vitro cytotoxicity investigation of CuI-FE was performed against cancer and spleen cell lines to evaluate the cell viability. Cytotoxicity analysis revealed the IC50 value of 233.93 μg/mL in the presence of CuI-FE. Molecular docking study was also carried out to understand the interaction of CuI-FE with COVID-19 main protease. This paper has given an insight on the usage of CuI-FE coated on the cotton fabric that has proved to have strong inhibition against the nano ranged bacterial, cancerous cell line and a strong interaction with the COVID-19 protease. Such eco-friendly material will provide a safe environment even after the disposable of medical waste from the infectious diseases like influenza and current pandemic like COVID-19. |
| first_indexed | 2024-12-22T00:46:09Z |
| format | Article |
| id | doaj.art-9e080fc6b1fc4c2eb86df8edef8353e2 |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-22T00:46:09Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-9e080fc6b1fc4c2eb86df8edef8353e22022-12-21T18:44:33ZengElsevierJournal of Materials Research and Technology2238-78542021-11-011521022116Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemicK.M. Archana0Revathy Rajagopal1Veena Gayathri Krishnaswamy2S. Aishwarya3Department of Chemistry, Stella Maris College (Autonomous), Affiliated to University of Madras, Chennai, IndiaDepartment of Chemistry, Stella Maris College (Autonomous), Affiliated to University of Madras, Chennai, India; Corresponding author.Department of Biotechnology, Stella Maris College (Autonomous), Affiliated to University of Madras, Chennai, India; Corresponding author.Department of Bioinformatics, Stella Maris College (Autonomous), Affiliated to University of Madras, Chennai, IndiaMicroorganisms cause variety of diseases that constitutes a severe threat to mankind. Due to the upsurge of many infectious diseases, there is a high requirement and demand for the development of safety products finished with antimicrobial properties. The study involves the antimicrobial activity of natural cotton coated with copper iodide capped with Hibiscus rosa-sinensis L. flower extract (CuI-FE) which is rich in anthocyanin, cyanidin-3-sophoroside by ultrasonication method. The coated and uncoated cotton fabric was characterised through XRD, SEM, AFM, tensile strength and UV–Visible spectroscopic techniques. XRD confirmed the formation of CuI particles, SEM showed that CuI-FE was prismatic in shape. The average size of CuI-FE particles was found to be 552.45 nm. Anti-bacterial studies showed copper iodide particles to be a potent antimicrobial agent. AFM images confirmed the rupture of bacterial cell walls in the presence of prismatic CuI-FE. In-vitro cytotoxicity investigation of CuI-FE was performed against cancer and spleen cell lines to evaluate the cell viability. Cytotoxicity analysis revealed the IC50 value of 233.93 μg/mL in the presence of CuI-FE. Molecular docking study was also carried out to understand the interaction of CuI-FE with COVID-19 main protease. This paper has given an insight on the usage of CuI-FE coated on the cotton fabric that has proved to have strong inhibition against the nano ranged bacterial, cancerous cell line and a strong interaction with the COVID-19 protease. Such eco-friendly material will provide a safe environment even after the disposable of medical waste from the infectious diseases like influenza and current pandemic like COVID-19.http://www.sciencedirect.com/science/article/pii/S2238785421010012Green synthesisCyanidin-3-sophorosideCuICotton fabricCovid-19 main protease |
| spellingShingle | K.M. Archana Revathy Rajagopal Veena Gayathri Krishnaswamy S. Aishwarya Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic Journal of Materials Research and Technology Green synthesis Cyanidin-3-sophoroside CuI Cotton fabric Covid-19 main protease |
| title | Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic |
| title_full | Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic |
| title_fullStr | Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic |
| title_full_unstemmed | Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic |
| title_short | Application of green synthesised copper iodide particles on cotton fabric-protective face mask material against COVID-19 pandemic |
| title_sort | application of green synthesised copper iodide particles on cotton fabric protective face mask material against covid 19 pandemic |
| topic | Green synthesis Cyanidin-3-sophoroside CuI Cotton fabric Covid-19 main protease |
| url | http://www.sciencedirect.com/science/article/pii/S2238785421010012 |
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