Current state and prospects of using dendritic cell vaccination for cancer immunotherapy
Recent advances in cancer immunotherapy have steadily increased the effectiveness of standard antitumor therapy methods. Due to their low toxicity and simple production process, personalized therapeutic vaccines based on dendritic cells are of particular clinical interest. A striking fact is that th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Kazan Federal University
2022-09-01
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| Series: | Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki |
| Subjects: | |
| Online Access: | https://kpfu.ru/uz-eng-ns-2022-3-1.html |
| _version_ | 1797826710378381312 |
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| author | I.Yu. Filin K.V. Kitaeva A.A. Rizvanov V.V. Solovyeva |
| author_facet | I.Yu. Filin K.V. Kitaeva A.A. Rizvanov V.V. Solovyeva |
| author_sort | I.Yu. Filin |
| collection | DOAJ |
| description | Recent advances in cancer immunotherapy have steadily increased the effectiveness of standard antitumor therapy methods. Due to their low toxicity and simple production process, personalized therapeutic vaccines based on dendritic cells are of particular clinical interest. A striking fact is that the first attempts to use such vaccines in clinical practice were discouraging. However, their scope and effectiveness were subsequently greatly enhanced by the development of new approaches to activating and loading dendritic cells with tumor-associated antigens, as well as by their use as an adjuvant in combination with other therapeutic methods for cancer treatment. This review considers new techniques and the latest achievements in the development of dendritic vaccines that ensure their clinical success. |
| first_indexed | 2024-04-09T12:36:41Z |
| format | Article |
| id | doaj.art-9e09c48c6681492a8c9ae1d983be7f4d |
| institution | Directory Open Access Journal |
| issn | 2542-064X 2500-218X |
| language | English |
| last_indexed | 2024-04-09T12:36:41Z |
| publishDate | 2022-09-01 |
| publisher | Kazan Federal University |
| record_format | Article |
| series | Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki |
| spelling | doaj.art-9e09c48c6681492a8c9ae1d983be7f4d2023-05-15T10:34:36ZengKazan Federal UniversityUčënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki2542-064X2500-218X2022-09-01164334736610.26907/2542-064X.2022.3.347-366Current state and prospects of using dendritic cell vaccination for cancer immunotherapyI.Yu. Filin0K.V. Kitaeva1A.A. Rizvanov2V.V. Solovyeva3Kazan Federal University, Kazan, 420008 RussiaKazan Federal University, Kazan, 420008 RussiaKazan Federal University, Kazan, 420008 RussiaKazan Federal University, Kazan, 420008 RussiaRecent advances in cancer immunotherapy have steadily increased the effectiveness of standard antitumor therapy methods. Due to their low toxicity and simple production process, personalized therapeutic vaccines based on dendritic cells are of particular clinical interest. A striking fact is that the first attempts to use such vaccines in clinical practice were discouraging. However, their scope and effectiveness were subsequently greatly enhanced by the development of new approaches to activating and loading dendritic cells with tumor-associated antigens, as well as by their use as an adjuvant in combination with other therapeutic methods for cancer treatment. This review considers new techniques and the latest achievements in the development of dendritic vaccines that ensure their clinical success.https://kpfu.ru/uz-eng-ns-2022-3-1.htmlimmunotherapycancerantitumor vaccinesdendritic cellsdendritic vaccinesantigen-presenting cells |
| spellingShingle | I.Yu. Filin K.V. Kitaeva A.A. Rizvanov V.V. Solovyeva Current state and prospects of using dendritic cell vaccination for cancer immunotherapy Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki immunotherapy cancer antitumor vaccines dendritic cells dendritic vaccines antigen-presenting cells |
| title | Current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| title_full | Current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| title_fullStr | Current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| title_full_unstemmed | Current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| title_short | Current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| title_sort | current state and prospects of using dendritic cell vaccination for cancer immunotherapy |
| topic | immunotherapy cancer antitumor vaccines dendritic cells dendritic vaccines antigen-presenting cells |
| url | https://kpfu.ru/uz-eng-ns-2022-3-1.html |
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