Combining OSMAC Approach and Untargeted Metabolomics for the Identification of New Glycolipids with Potent Antiviral Activity Produced by a Marine <i>Rhodococcus</i>

Combining OSMAC Approach and Untargeted Metabolomics for the Identification of New Glycolipids with Potent Antiviral Activity Produced by a Marine <i>Rhodococcus</i>

Natural products of microbial origin have inspired most of the commercial pharmaceuticals, especially those from Actinobacteria. However, the redundancy of molecules in the discovery process represents a serious issue. The untargeted approach, One Strain Many Compounds (OSMAC), is one of the most pr...

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Bibliographic Details
Main Authors: Fortunato Palma Esposito, Rosa Giugliano, Gerardo Della Sala, Giovanni Andrea Vitale, Carmine Buonocore, Janardhan Ausuri, Christian Galasso, Daniela Coppola, Gianluigi Franci, Massimiliano Galdiero, Donatella de Pascale
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
trehalolipids
glycolipids
antiviral
antiproliferative
biosurfactant
marine bacteria
Online Access:https://www.mdpi.com/1422-0067/22/16/9055

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