Genomic basis for early-life mortality in sharpsnout seabream
Abstract Mortality at early life stages of fishes is common in nature and can be shaped by stochastic and selective processes. Selective mortality has rarely been assessed in natural conditions but can now be studied by combining genomic data with information on different life stages that realates t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-21597-3 |
| _version_ | 1811182231726587904 |
|---|---|
| author | Héctor Torrado Cinta Pegueroles Nuria Raventos Carlos Carreras Enrique Macpherson Marta Pascual |
| author_facet | Héctor Torrado Cinta Pegueroles Nuria Raventos Carlos Carreras Enrique Macpherson Marta Pascual |
| author_sort | Héctor Torrado |
| collection | DOAJ |
| description | Abstract Mortality at early life stages of fishes is common in nature and can be shaped by stochastic and selective processes. Selective mortality has rarely been assessed in natural conditions but can now be studied by combining genomic data with information on different life stages that realates to fitness. Here we investigate selective mortality between settlers and six-month survivors of the sharpsnout seabream by genotype-phenotype/environmental association studies in three localities along a geographic gradient. We gathered information on 105 individuals at 85,031 SNPs, obtained from individual based 2b-RAD libraries, as well as 9 phenotypic and environmental variables derived from individual otolith readings. We found common signals across localities for potential selection, such as lower survival rates for individuals hatching earlier, growing faster and experiencing higher temperatures during their planktonic phase. We identified 122 loci with parallel significant association to phenotypic and environmental variables. Importantly, one of these loci mapped to the exonic region of the il20rb, a gene involved in immune response, in the phylogenetically closest reference genome, showing parallel frequency changes in non-synonymous mutations in the three studied populations. Further temporal assessments are needed to understand how polymorphisms that are key to selective mortality are maintained. |
| first_indexed | 2024-04-11T09:29:10Z |
| format | Article |
| id | doaj.art-9e0bafeed8ac4771b4377db6c2a2e601 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T09:29:10Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-9e0bafeed8ac4771b4377db6c2a2e6012022-12-22T04:31:57ZengNature PortfolioScientific Reports2045-23222022-10-0112111110.1038/s41598-022-21597-3Genomic basis for early-life mortality in sharpsnout seabreamHéctor Torrado0Cinta Pegueroles1Nuria Raventos2Carlos Carreras3Enrique Macpherson4Marta Pascual5Centre d’Estudis Avançats de Blanes (CEAB-CSIC)Department of Genetics, Microbiology and Statistics, and Institute for Research on Biodiversity (IRBio), University of BarcelonaCentre d’Estudis Avançats de Blanes (CEAB-CSIC)Department of Genetics, Microbiology and Statistics, and Institute for Research on Biodiversity (IRBio), University of BarcelonaCentre d’Estudis Avançats de Blanes (CEAB-CSIC)Department of Genetics, Microbiology and Statistics, and Institute for Research on Biodiversity (IRBio), University of BarcelonaAbstract Mortality at early life stages of fishes is common in nature and can be shaped by stochastic and selective processes. Selective mortality has rarely been assessed in natural conditions but can now be studied by combining genomic data with information on different life stages that realates to fitness. Here we investigate selective mortality between settlers and six-month survivors of the sharpsnout seabream by genotype-phenotype/environmental association studies in three localities along a geographic gradient. We gathered information on 105 individuals at 85,031 SNPs, obtained from individual based 2b-RAD libraries, as well as 9 phenotypic and environmental variables derived from individual otolith readings. We found common signals across localities for potential selection, such as lower survival rates for individuals hatching earlier, growing faster and experiencing higher temperatures during their planktonic phase. We identified 122 loci with parallel significant association to phenotypic and environmental variables. Importantly, one of these loci mapped to the exonic region of the il20rb, a gene involved in immune response, in the phylogenetically closest reference genome, showing parallel frequency changes in non-synonymous mutations in the three studied populations. Further temporal assessments are needed to understand how polymorphisms that are key to selective mortality are maintained.https://doi.org/10.1038/s41598-022-21597-3 |
| spellingShingle | Héctor Torrado Cinta Pegueroles Nuria Raventos Carlos Carreras Enrique Macpherson Marta Pascual Genomic basis for early-life mortality in sharpsnout seabream Scientific Reports |
| title | Genomic basis for early-life mortality in sharpsnout seabream |
| title_full | Genomic basis for early-life mortality in sharpsnout seabream |
| title_fullStr | Genomic basis for early-life mortality in sharpsnout seabream |
| title_full_unstemmed | Genomic basis for early-life mortality in sharpsnout seabream |
| title_short | Genomic basis for early-life mortality in sharpsnout seabream |
| title_sort | genomic basis for early life mortality in sharpsnout seabream |
| url | https://doi.org/10.1038/s41598-022-21597-3 |
| work_keys_str_mv | AT hectortorrado genomicbasisforearlylifemortalityinsharpsnoutseabream AT cintapegueroles genomicbasisforearlylifemortalityinsharpsnoutseabream AT nuriaraventos genomicbasisforearlylifemortalityinsharpsnoutseabream AT carloscarreras genomicbasisforearlylifemortalityinsharpsnoutseabream AT enriquemacpherson genomicbasisforearlylifemortalityinsharpsnoutseabream AT martapascual genomicbasisforearlylifemortalityinsharpsnoutseabream |