p16 mutation spectrum in the premalignant condition Barrett's esophagus.

p16 mutation spectrum in the premalignant condition Barrett's esophagus.

Mutation, promoter hypermethylation and loss of heterozygosity involving the tumor suppressor gene p16 (CDKN2a/INK4a) have been detected in a wide variety of human cancers, but much less is known concerning the frequency and spectrum of p16 mutations in premalignant conditions.We have determined the...

书目详细资料
Main Authors:	Thomas G Paulson, Patricia C Galipeau, Lianjun Xu, Heather D Kissel, Xiaohong Li, Patricia L Blount, Carissa A Sanchez, Robert D Odze, Brian J Reid
格式:	文件
语言:	English
出版:	Public Library of Science (PLoS) 2008-01-01
丛编:	PLoS ONE
在线阅读:	http://europepmc.org/articles/PMC2585012?pdf=render

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