Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy
Diabetic nephropathy (DN) is a serious microvascular complication in diabetes mellitus patients and 30–45% of DN patients progresses to end-stage renal disease, imposing a heavy burden on the society. Unfortunately, the pathogenesis of DN remains unclear, and effective and safe therapies are in grea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-04-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464615000389 |
| _version_ | 1818417875670532096 |
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| author | Jing-Yi Liu Xiao-Xin Chen Sydney Chi-Wai Tang Li-Xing Lao Stephen Cho-Wing Sze Kai-Fai Lee Kalin Yan-Bo Zhang |
| author_facet | Jing-Yi Liu Xiao-Xin Chen Sydney Chi-Wai Tang Li-Xing Lao Stephen Cho-Wing Sze Kai-Fai Lee Kalin Yan-Bo Zhang |
| author_sort | Jing-Yi Liu |
| collection | DOAJ |
| description | Diabetic nephropathy (DN) is a serious microvascular complication in diabetes mellitus patients and 30–45% of DN patients progresses to end-stage renal disease, imposing a heavy burden on the society. Unfortunately, the pathogenesis of DN remains unclear, and effective and safe therapies are in great demand. Rather than conventional medicines that concentrate on delaying renal failure by controlling blood sugar and/or ameliorating microalbuminuria, traditional Chinese medicine (TCM) emphasize on the patients' whole inner system and devote to repair the kidney with consideration of overall health. Since many TCM herbs are edible, edible plants from TCM as diet therapy would be a promising alternative for DN management. To date, remarkable progresses have been made on the therapeutic effects of TCM edible plants for DN. In this review, the pathogenesis and experimental models of DN are firstly discussed. Thereafter, the structures of active components from TCM edible plants are summarized followed by discussion of recent research on TCM edible plants as functional food for diet therapy. Additionally, the necessity for safety evaluation of TCM edible plants for DN treatment is addressed. |
| first_indexed | 2024-12-14T12:13:44Z |
| format | Article |
| id | doaj.art-9e1621ecb91f44fca0bf6348ea44d43a |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-14T12:13:44Z |
| publishDate | 2015-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-9e1621ecb91f44fca0bf6348ea44d43a2022-12-21T23:01:41ZengElsevierJournal of Functional Foods1756-46462015-04-01141222Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathyJing-Yi Liu0Xiao-Xin Chen1Sydney Chi-Wai Tang2Li-Xing Lao3Stephen Cho-Wing Sze4Kai-Fai Lee5Kalin Yan-Bo Zhang6School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong KongSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong KongDepartment of Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong Kong; Corresponding author. Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong Kong. Tel: +852 22553879; fax: +852 28725828.School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong KongSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong KongObstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong KongSchool of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong Kong; Corresponding author. School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Hong Kong. Tel: +852 25890481; fax: +852 28725476.Diabetic nephropathy (DN) is a serious microvascular complication in diabetes mellitus patients and 30–45% of DN patients progresses to end-stage renal disease, imposing a heavy burden on the society. Unfortunately, the pathogenesis of DN remains unclear, and effective and safe therapies are in great demand. Rather than conventional medicines that concentrate on delaying renal failure by controlling blood sugar and/or ameliorating microalbuminuria, traditional Chinese medicine (TCM) emphasize on the patients' whole inner system and devote to repair the kidney with consideration of overall health. Since many TCM herbs are edible, edible plants from TCM as diet therapy would be a promising alternative for DN management. To date, remarkable progresses have been made on the therapeutic effects of TCM edible plants for DN. In this review, the pathogenesis and experimental models of DN are firstly discussed. Thereafter, the structures of active components from TCM edible plants are summarized followed by discussion of recent research on TCM edible plants as functional food for diet therapy. Additionally, the necessity for safety evaluation of TCM edible plants for DN treatment is addressed.http://www.sciencedirect.com/science/article/pii/S1756464615000389Diabetic nephropathyTraditional Chinese medicineEdible plantsActive componentsDiet therapy |
| spellingShingle | Jing-Yi Liu Xiao-Xin Chen Sydney Chi-Wai Tang Li-Xing Lao Stephen Cho-Wing Sze Kai-Fai Lee Kalin Yan-Bo Zhang Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy Journal of Functional Foods Diabetic nephropathy Traditional Chinese medicine Edible plants Active components Diet therapy |
| title | Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy |
| title_full | Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy |
| title_fullStr | Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy |
| title_full_unstemmed | Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy |
| title_short | Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy |
| title_sort | edible plants from traditional chinese medicine is a promising alternative for the management of diabetic nephropathy |
| topic | Diabetic nephropathy Traditional Chinese medicine Edible plants Active components Diet therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1756464615000389 |
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