Liver Metabolomics and Inflammatory Profiles in Mouse Model of Fentanyl Overdose Treated with Beta-Lactams

Liver Metabolomics and Inflammatory Profiles in Mouse Model of Fentanyl Overdose Treated with Beta-Lactams

Fentanyl is a highly potent opioid analgesic that is approved medically to treat acute and chronic pain. There is a high potential for overdose-induced organ toxicities, including liver toxicity, and this might be due to the increase of recreational use of opioids. Several preclinical studies have d...

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Bibliographic Details
Main Authors: Fawaz Alasmari, Mohammed S. Alasmari, Mohammed A. Assiri, Mohammed Alswayyed, Syed Rizwan Ahamad, Abdulrahman I. Alhumaydhi, Bandar I. Arif, Sahar R. Aljumayi, Abdullah F. AlAsmari, Nemat Ali, Wayne E. Childers, Magid Abou-Gharbia, Youssef Sari
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Metabolites
Subjects:
opioids
overdose
beta-lactams
ceftriaxone
MC-100093
metabolomic
Online Access:https://www.mdpi.com/2218-1989/13/8/965

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