Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications

In this study, we fabricated Poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) nanofibres using electrospinning and evaluated their potential use for bone repair applications. Analysis confirmed that the PLGA nanofibres were similar to the natural extracellular matrix and included HAp particles....

Full description

Bibliographic Details
Main Authors: S.Y. Heo, J.W. Seol, N.S. Kim
Format: Article
Language:English
Published: Czech Academy of Agricultural Sciences 2014-10-01
Series:Veterinární Medicína
Subjects:
Online Access:https://vetmed.agriculturejournals.cz/artkey/vet-201410-0004_characterisation-and-assessment-of-electrospun-poly-hydroxyapatite-nanofibres-together-with-a-cell-adhesive-for.php
_version_ 1797897600682164224
author S.Y. Heo
J.W. Seol
N.S. Kim
author_facet S.Y. Heo
J.W. Seol
N.S. Kim
author_sort S.Y. Heo
collection DOAJ
description In this study, we fabricated Poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) nanofibres using electrospinning and evaluated their potential use for bone repair applications. Analysis confirmed that the PLGA nanofibres were similar to the natural extracellular matrix and included HAp particles. Further, gelatin augmented the adhesion of electrospun nanofibres in the cell adhesion test. Therefore, electrospun PLGA/HAp nanofibres together with gelatin can be utilised for bone repair applications.
first_indexed 2024-04-10T07:59:54Z
format Article
id doaj.art-9e26a1bcbdd647988cdffb1c2371f5b7
institution Directory Open Access Journal
issn 0375-8427
1805-9392
language English
last_indexed 2024-04-10T07:59:54Z
publishDate 2014-10-01
publisher Czech Academy of Agricultural Sciences
record_format Article
series Veterinární Medicína
spelling doaj.art-9e26a1bcbdd647988cdffb1c2371f5b72023-02-23T03:50:16ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922014-10-01591049850110.17221/7780-VETMEDvet-201410-0004Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applicationsS.Y. Heo0J.W. Seol1N.S. Kim2College of Veterinary Medicine, Chonbuk National University, Jeonju, Republic of KoreaCollege of Veterinary Medicine, Chonbuk National University, Jeonju, Republic of KoreaCollege of Veterinary Medicine, Chonbuk National University, Jeonju, Republic of KoreaIn this study, we fabricated Poly(lactide-co-glycolide)/hydroxyapatite (PLGA/HAp) nanofibres using electrospinning and evaluated their potential use for bone repair applications. Analysis confirmed that the PLGA nanofibres were similar to the natural extracellular matrix and included HAp particles. Further, gelatin augmented the adhesion of electrospun nanofibres in the cell adhesion test. Therefore, electrospun PLGA/HAp nanofibres together with gelatin can be utilised for bone repair applications.https://vetmed.agriculturejournals.cz/artkey/vet-201410-0004_characterisation-and-assessment-of-electrospun-poly-hydroxyapatite-nanofibres-together-with-a-cell-adhesive-for.phppoly(lactide-co-glycolide)hydroxyapatitenanofibreelectrospinninggelatin
spellingShingle S.Y. Heo
J.W. Seol
N.S. Kim
Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
Veterinární Medicína
poly(lactide-co-glycolide)
hydroxyapatite
nanofibre
electrospinning
gelatin
title Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
title_full Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
title_fullStr Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
title_full_unstemmed Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
title_short Characterisation and assessment of electrospun Poly/hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
title_sort characterisation and assessment of electrospun poly hydroxyapatite nanofibres together with a cell adhesive for bone repair applications
topic poly(lactide-co-glycolide)
hydroxyapatite
nanofibre
electrospinning
gelatin
url https://vetmed.agriculturejournals.cz/artkey/vet-201410-0004_characterisation-and-assessment-of-electrospun-poly-hydroxyapatite-nanofibres-together-with-a-cell-adhesive-for.php
work_keys_str_mv AT syheo characterisationandassessmentofelectrospunpolyhydroxyapatitenanofibrestogetherwithacelladhesiveforbonerepairapplications
AT jwseol characterisationandassessmentofelectrospunpolyhydroxyapatitenanofibrestogetherwithacelladhesiveforbonerepairapplications
AT nskim characterisationandassessmentofelectrospunpolyhydroxyapatitenanofibrestogetherwithacelladhesiveforbonerepairapplications