CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS
Aim: To present modern approaches to the systemic therapy by glucocorticosteroids (GCS) basing on own experience and literature data. Methods and material: Long-term observation of 350 patients with juvenile rheumatoid arthritis (JRA) taking peroral GCS in different dosage. Results: Good therapeutic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2000-04-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1140 |
| _version_ | 1826556406707257344 |
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| author | N N Kuzmina B P Shokh I L Nikishina |
| author_facet | N N Kuzmina B P Shokh I L Nikishina |
| author_sort | N N Kuzmina |
| collection | DOAJ |
| description | Aim: To present modern approaches to the systemic therapy by glucocorticosteroids (GCS) basing on own experience and literature data. Methods and material: Long-term observation of 350 patients with juvenile rheumatoid arthritis (JRA) taking peroral GCS in different dosage. Results: Good therapeutical efficacy and sufficient tolerability of low starting doses (lower than 0.5 mg/ kg a day) of GCS allow to inhibit inflammatory activity in the majority of patients. Alternative method (doses alternation) is recommended in the period of long-term supporting GCS-therapv of JR.4. Conclusion: Basic strategy of treatment of systemic and polyarticular JRA j'orms is rational GCS application in combination with basic drugs which ensures control of pathologic process and modifies the disease. |
| first_indexed | 2024-04-09T22:30:46Z |
| format | Article |
| id | doaj.art-9e26f2f108fb443f840575f2a8795426 |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2025-03-14T08:12:12Z |
| publishDate | 2000-04-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-9e26f2f108fb443f840575f2a87954262025-03-02T13:23:20ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922000-04-01382566210.14412/1995-4484-2000-12341080CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITISN N KuzminaB P ShokhI L NikishinaAim: To present modern approaches to the systemic therapy by glucocorticosteroids (GCS) basing on own experience and literature data. Methods and material: Long-term observation of 350 patients with juvenile rheumatoid arthritis (JRA) taking peroral GCS in different dosage. Results: Good therapeutical efficacy and sufficient tolerability of low starting doses (lower than 0.5 mg/ kg a day) of GCS allow to inhibit inflammatory activity in the majority of patients. Alternative method (doses alternation) is recommended in the period of long-term supporting GCS-therapv of JR.4. Conclusion: Basic strategy of treatment of systemic and polyarticular JRA j'orms is rational GCS application in combination with basic drugs which ensures control of pathologic process and modifies the disease.https://rsp.mediar-press.net/rsp/article/view/1140basic drugsjralow gcs doses |
| spellingShingle | N N Kuzmina B P Shokh I L Nikishina CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS Научно-практическая ревматология basic drugs jra low gcs doses |
| title | CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS |
| title_full | CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS |
| title_fullStr | CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS |
| title_full_unstemmed | CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS |
| title_short | CURRENT VIEW ON SYSTEMIC GLUCOCORTICOSTEROID THERAPY IN JUVENILE RHEUMATOID ARTHRITIS |
| title_sort | current view on systemic glucocorticosteroid therapy in juvenile rheumatoid arthritis |
| topic | basic drugs jra low gcs doses |
| url | https://rsp.mediar-press.net/rsp/article/view/1140 |
| work_keys_str_mv | AT nnkuzmina currentviewonsystemicglucocorticosteroidtherapyinjuvenilerheumatoidarthritis AT bpshokh currentviewonsystemicglucocorticosteroidtherapyinjuvenilerheumatoidarthritis AT ilnikishina currentviewonsystemicglucocorticosteroidtherapyinjuvenilerheumatoidarthritis |